SCHEMBL5721286

SCHEMBL5721286

CC1=Cc2c(ccc(-c3ccccc3)c2-c2ccccc2C(C)C)C1[Zr](Cl)Cl

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
PTPN5 P54829 1/20 0.31
ALDH1A1 P00352 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5721632 0.88 CA12 (0.32) CA12CA1CA2CA9PTPN5
SCHEMBL5721633 0.88 FAAH (0.31) CA1CA2TSHR
SCHEMBL5609628 0.87 PDCD1 (0.30)
SCHEMBL5721550 0.87
SCHEMBL5721543 0.86 DHFR (0.31) CA12CA1CA2CA9
SCHEMBL5721347 0.85 PTPN5 (0.31) PTPN5
SCHEMBL5721841 0.85 FFAR1 (0.30)
SCHEMBL5721888 0.85 NPC1 (0.33) ALDH1A1TSHR
SCHEMBL6911025 0.85
SCHEMBL5721704 0.84 PPARA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1640377-A1 Metallocenes and catalyst compositions derived therefrom Exxonmobil Chemical Patents Inc. (US) 2006-03-29 EP disclosed