SCHEMBL5721292

SCHEMBL5721292

CCCCC1=Cc2c(ccc(-c3ccccc3)c2-c2ccccc2-c2ccccc2)[CH]1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 1/20 0.35
SOAT1 P35610 2/20 0.32
DHFR P00374 1/20 0.32
HSD11B1 P28845 1/20 0.31
GCGR P47871 1/20 0.31
GPR3 P46089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5721791 0.92 ADRB2 (0.30)
SCHEMBL5721362 0.91 PSMB5 (0.36) PSMB5HSD11B1GCGR
SCHEMBL5721690 0.90 PSMB5 (0.33) PSMB5SOAT1GCGR
SCHEMBL5721422 0.90 PSMB5 (0.36) PSMB5SOAT1DHFRHSD11B1GCGR
SCHEMBL5610318 0.88 PSMB5 (0.33) PSMB5SOAT1GCGR
SCHEMBL5721606 0.88 PSMB5 (0.33) PSMB5
SCHEMBL5721120 0.86 PSMB5 (0.32) PSMB5
SCHEMBL5721901 0.86 GCGR (0.34) PSMB5GCGR
SCHEMBL5721356 0.86 PTGS2 (0.30)
SCHEMBL6376457 0.83 PSMB5 (0.38) PSMB5SOAT1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1640377-A1 Metallocenes and catalyst compositions derived therefrom Exxonmobil Chemical Patents Inc. (US) 2006-03-29 EP disclosed