Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.51 |
| ▸ | PPARA | Q07869 | 6/20 | 0.51 |
| ▸ | PPARD | Q03181 | 5/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3960321 | 1.00 | PPARG (0.51) | PPARGPPARAPPARDCYP2D6EPHX2 | |
| SCHEMBL3960331 | 1.00 | PPARG (0.51) | PPARGPPARAPPARDCYP2D6EPHX2 | |
| SCHEMBL5372547 | 1.00 | PPARG (0.51) | PPARGPPARAPPARDCYP2D6EPHX2 | |
| SCHEMBL3960715 | 0.84 | ALDH1A1 (0.60) | PPARGPPARAPPARDMEN1ALDH1A1 | |
| SCHEMBL3960707 | 0.84 | ALDH1A1 (0.60) | PPARGPPARAPPARDMEN1ALDH1A1 | |
| SCHEMBL3968494 | 0.84 | ALDH1A1 (0.60) | PPARGPPARAPPARDMEN1ALDH1A1 | |
| SCHEMBL5358355 | 0.84 | ALDH1A1 (0.60) | PPARGPPARAPPARDMEN1ALDH1A1 | |
| SCHEMBL3968491 | 0.84 | ALDH1A1 (0.60) | PPARGPPARAPPARDMEN1ALDH1A1 | |
| SCHEMBL3965041 | 0.81 | PPARG (0.51) | PPARGPPARAPPARDMEN1LMNA | |
| SCHEMBL3965050 | 0.81 | PPARG (0.51) | PPARGPPARAPPARDMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675820-A2 | PROPIONIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF LIPID DISORDERS | AstraZeneca AB (SE) | 2006-07-05 | — | — | EP | disclosed |
| WO-2004113270-A2 | PROPIONIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF LIPID DISORDERS | ASTRAZENECA AB (SE) | 2004-12-29 | — | — | WO | disclosed |