Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 3/20 | 0.57 |
| ▸ | PPARD | Q03181 | 3/20 | 0.57 |
| ▸ | PPARA | Q07869 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3960707 | 1.00 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1PPARGPPARD | |
| SCHEMBL3968494 | 1.00 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1PPARGPPARD | |
| SCHEMBL3968491 | 1.00 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1PPARGPPARD | |
| SCHEMBL3960715 | 1.00 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1PPARGPPARD | |
| SCHEMBL3960321 | 0.84 | PPARG (0.51) | ALDH1A1KMT2AMEN1PPARGPPARD | |
| SCHEMBL3960331 | 0.84 | PPARG (0.51) | ALDH1A1KMT2AMEN1PPARGPPARD | |
| SCHEMBL5721701 | 0.84 | PPARG (0.51) | ALDH1A1KMT2AMEN1PPARGPPARD | |
| SCHEMBL5372547 | 0.84 | PPARG (0.51) | ALDH1A1KMT2AMEN1PPARGPPARD | |
| SCHEMBL5364273 | 0.84 | GPR34 (0.54) | ALDH1A1KMT2AMEN1PPARGPPARD | |
| SCHEMBL3959707 | 0.84 | GPR34 (0.54) | ALDH1A1KMT2AMEN1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220880-B2 | Amide linker peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2007-05-22 | — | — | US | claimed |
| US-20060111406-A1 | Amide linker peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2006-05-25 | — | — | US | claimed |
| US-7220880-B2 | Amide linker peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2007-05-22 | — | — | US | disclosed |
| US-20060111406-A1 | Amide linker peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2006-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111406-A1 | Amide linker peroxisome proliferator activated receptor modulators | PPARG, PPARA, PPARD | ALDH1A1 840/4885KMT2A 2361/4885MEN1 4823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.