Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5721519 | 0.91 | ELANE (0.32) | PDK2 | |
| SCHEMBL5721719 | 0.90 | PDK2 (0.31) | PDK2TRPA1 | |
| SCHEMBL5721654 | 0.88 | DHFR (0.34) | PDK2GABRA1GABRB2TRPA1LMNA | |
| SCHEMBL5721200 | 0.88 | HEXA (0.35) | PDK2 | |
| SCHEMBL5721298 | 0.87 | ELANE (0.31) | PDK2 | |
| SCHEMBL5721305 | 0.87 | ELANE (0.33) | PDK2 | |
| SCHEMBL5721375 | 0.87 | PTGS2 (0.32) | PDK2PTPN5 | |
| SCHEMBL5721369 | 0.85 | PTPN5 (0.35) | PDK2TRPA1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL5721699 | 0.85 | ELANE (0.32) | — | |
| SCHEMBL5721577 | 0.84 | PDK2 (0.33) | PDK2TRPA1LMNACSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1640377-A1 | Metallocenes and catalyst compositions derived therefrom | Exxonmobil Chemical Patents Inc. (US) | 2006-03-29 | — | — | EP | disclosed |