SCHEMBL5721736

SCHEMBL5721736

CCCCC1=Cc2c(ccc(C)c2-c2ccccc2C)[CH]1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HEXA P06865 1/20 0.34
HEXB P07686 1/20 0.34
TLR8 Q9NR97 1/20 0.33
HTR7 P34969 1/20 0.33
SKP2 Q13309 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5721177 0.88 TLR8 (0.33) TLR8SKP2
SCHEMBL5721422 0.88 PSMB5 (0.36) HTR7SKP2
SCHEMBL5721362 0.87 PSMB5 (0.36) HEXAHEXBHTR7
SCHEMBL5721152 0.85 HEXA (0.40) HEXAHEXB
SCHEMBL5721551 0.81 HEXA (0.31) HEXAHEXB
SCHEMBL5721525 0.80
SCHEMBL5721742 0.80 DHFR (0.32)
SCHEMBL5721804 0.79 HEXA (0.32) HEXAHEXB
SCHEMBL5721533 0.78 NPC1 (0.33) HEXAHEXBHTR7
SCHEMBL5721305 0.77 ELANE (0.33) TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1640377-A1 Metallocenes and catalyst compositions derived therefrom Exxonmobil Chemical Patents Inc. (US) 2006-03-29 EP disclosed