SCHEMBL5721152

SCHEMBL5721152

CCC1=Cc2c(ccc(C)c2-c2ccccc2C)[CH]1

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HEXA P06865 1/20 0.40
HEXB P07686 1/20 0.40
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5721654 0.88 DHFR (0.34) HEXAHEXB
SCHEMBL5721200 0.88 HEXA (0.35) HEXAHEXBPTGS1PTGS2
SCHEMBL5721694 0.87 PDCD1 (0.31)
SCHEMBL5721611 0.85 HEXA (0.37) HEXAHEXBPTGS1PTGS2
SCHEMBL5721736 0.85 HEXA (0.34) HEXAHEXB
SCHEMBL5721641 0.84 DHFR (0.32)
SCHEMBL5721804 0.84 HEXA (0.32) HEXAHEXB
SCHEMBL27446349 0.81 HTR7 (0.35) HEXAHEXB
SCHEMBL5721167 0.80 HEXA (0.34) HEXAHEXBPTGS1PTGS2
SCHEMBL5721742 0.79 DHFR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1640377-A1 Metallocenes and catalyst compositions derived therefrom Exxonmobil Chemical Patents Inc. (US) 2006-03-29 EP disclosed