Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 17/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30045 | 0.89 | EPHX2 (0.57) | EPHX2FAAHADRB2 | |
| SCHEMBL9572108 | 0.89 | EPHX2 (0.57) | EPHX2FAAHADRB2 | |
| SCHEMBL9572112 | 0.89 | EPHX2 (0.57) | EPHX2FAAHADRB2 | |
| SCHEMBL16242402 | 0.81 | EPHX2 (0.58) | EPHX2FAAHADRB2 | |
| SCHEMBL17123795 | 0.81 | EPHX2 (0.54) | EPHX2FAAHADRB2 | |
| SCHEMBL1065749 | 0.80 | EPHX2 (0.50) | EPHX2FAAHADRB2 | |
| SCHEMBL9774780 | 0.80 | EPHX2 (0.54) | EPHX2FAAHADRB2 | |
| SCHEMBL1065750 | 0.80 | EPHX2 (0.50) | EPHX2FAAHADRB2 | |
| SCHEMBL15574818 | 0.80 | EPHX2 (0.50) | EPHX2FAAHADRB2 | |
| SCHEMBL5722066 | 0.80 | EPHX2 (0.50) | EPHX2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716100-A2 | THERAPEUTIC AMIDE DERIVATIVES | Pfizer, Inc. (US) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005080317-A2 | THERAPEUTIC AMIDE DERIVATIVES | PFIZER JAPAN, INC. (JP) | 2005-09-01 | — | — | WO | disclosed |