Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 16/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9572112 | 1.00 | EPHX2 (0.57) | EPHX2FAAHHRH1PARP10ADRB2 | |
| SCHEMBL9572108 | 1.00 | EPHX2 (0.57) | EPHX2FAAHHRH1PARP10ADRB2 | |
| SCHEMBL17123795 | 0.91 | EPHX2 (0.54) | EPHX2FAAHPARP10ADRB2 | |
| SCHEMBL16242402 | 0.91 | EPHX2 (0.58) | EPHX2FAAHPARP10ADRB2 | |
| SCHEMBL5722064 | 0.89 | EPHX2 (0.50) | EPHX2FAAHADRB2 | |
| SCHEMBL1065749 | 0.89 | EPHX2 (0.50) | EPHX2FAAHPARP10ADRB2 | |
| SCHEMBL15574818 | 0.89 | EPHX2 (0.50) | EPHX2FAAHPARP10ADRB2 | |
| SCHEMBL1065750 | 0.89 | EPHX2 (0.50) | EPHX2FAAHPARP10ADRB2 | |
| SCHEMBL5722066 | 0.89 | EPHX2 (0.50) | EPHX2FAAH | |
| SCHEMBL9774780 | 0.89 | EPHX2 (0.54) | EPHX2FAAHADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088796-A | Method for synthesizing beta-trifluoromethylthioketone derivative by ring opening of cyclopropyl alcohol derivative | 天津师范大学 | 2023-11-21 | — | — | CN | disclosed |
| US-9241487-B2 | Pyrimidine derivatives and use thereof as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-01-26 | — | — | US | disclosed |
| US-9198429-B2 | Heterocyclic alkanol-derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-01 | — | — | US | disclosed |
| US-9095136-B2 | 2-IODO imidazole-derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-08-04 | — | — | US | disclosed |
| EP-2609088-B1 | 5-IODO-TRIAZOLE DERIVATIVES | BAYER IP GMBH (DE) | 2015-04-29 | — | — | EP | disclosed |
| US-8969248-B2 | 5-iodotriazole derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-03 | — | — | US | disclosed |
| US-20140336232-A1 | 2-IODO IMIDAZOLE-DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-11-13 | — | — | US | disclosed |
| US-20140274952-A1 | NOVEL HETEROCYCLIC ALKANOL-DERIVATIVES | BAYER INTELLCTUAL PROPERTY GMBH (DE) | 2014-09-18 | — | — | US | disclosed |
| US-20140031373-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS PESTICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-30 | — | — | US | disclosed |
| EP-2646418-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS PESTICIDES | Bayer Intellectual Property GmbH (DE) | 2013-10-09 | — | — | EP | disclosed |
| EP-2609088-A1 | 5-IODO-TRIAZOLE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2013-07-03 | — | — | EP | disclosed |
| US-20120220638-A1 | 5-Iodotriazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-08-30 | — | — | US | disclosed |
| WO-2012072547-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-07 | — | — | WO | disclosed |
| WO-2012025506-A1 | 5-IODO-TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336232-A1 | 2-IODO IMIDAZOLE-DERIVATIVES | CIP2A, ING2, AZI2 | EPHX2 3537/4885FAAH 3880/4885HRH1 3726/4885 |
| US-20140031373-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS PESTICIDES | TYMP, TYMS, UMPS | EPHX2 710/4885FAAH 3329/4885HRH1 3187/4885 |
| US-20120220638-A1 | 5-Iodotriazole derivatives | INMT, IGFBP5, HDHD5 | EPHX2 3432/4885FAAH 3752/4885HRH1 4518/4885 |
| US-20140274952-A1 | NOVEL HETEROCYCLIC ALKANOL-DERIVATIVES | ERG28, CBR3, MYB | EPHX2 1398/4885FAAH 317/4885HRH1 1291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.