Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.52 |
| ▸ | MGAM | O43451 | 2/20 | 0.52 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.52 |
| ▸ | SI | P14410 | 2/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.52 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ATM | Q13315 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722002 | 0.72 | MGAM (0.46) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL30407980 | 0.70 | KMT2A (0.46) | GAAKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL5722036 | 0.70 | MGAM (0.44) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL5154435 | 0.69 | CXCR3 (0.54) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL6399605 | 0.68 | MEN1 (0.74) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL5722034 | 0.67 | MGAM (0.40) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL5722070 | 0.67 | MEN1 (0.63) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL6399732 | 0.67 | CA1 (0.47) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL14373497 | 0.65 | CXCR3 (1.00) | GAACXCR3KMT2AATMNPC1 | |
| SCHEMBL6400580 | 0.64 | MEN1 (0.62) | GAAMGAMAMY1ASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554253-A4 | IMIDAZOLIUM CXCR3 INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2006-09-20 | — | — | EP | disclosed |
| US-20050272936-A1 | Imidazolium cxcr3 inhibitors | SMITHKLINE BEECHAM CORPORATION | 2005-12-08 | — | — | US | disclosed |
| EP-1554253-A1 | IMIDAZOLIUM CXCR3 INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-07-20 | — | — | EP | disclosed |
| WO-2003101970-A1 | IMIDAZOLIUM CXCR3 INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272936-A1 | Imidazolium cxcr3 inhibitors | CXCR3, CXCR1, CCR7 | GAA 4786/4885MGAM 4836/4885AMY1A 4686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.