Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | MGAM | O43451 | 2/20 | 0.52 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.52 |
| ▸ | SI | P14410 | 2/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18313849 | 0.78 | KDM4E (0.60) | NPC1RAB9AGAAMGAMAMY1A | |
| SCHEMBL3719707 | 0.71 | KDM4E (0.53) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL5722074 | 0.70 | ALPG (0.69) | CXCR3ATMMEN1KMT2ANPC1 | |
| SCHEMBL5721969 | 0.70 | CA12 (0.53) | CXCR3ATMMEN1KMT2ANPC1 | |
| SCHEMBL14373497 | 0.70 | CXCR3 (1.00) | CXCR3ATMMEN1KMT2ANPC1 | |
| SCHEMBL23440108 | 0.69 | ATM (0.74) | CXCR3ATMMEN1KMT2ANPC1 | |
| SCHEMBL5722076 | 0.69 | GAA (0.52) | CXCR3ATMMEN1KMT2ANPC1 | |
| SCHEMBL5722026 | 0.69 | CA12 (0.73) | CXCR3ATMMEN1KMT2ANPC1 | |
| SCHEMBL9015106 | 0.69 | TSHR (0.61) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL17966245 | 0.68 | ALDH1A1 (0.53) | CXCR3ATMMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463820-A4 | METHOD OF SCREENING COMPOUNDS | CHILDRENS MEDICAL CENTER (US) | 2007-09-05 | — | — | EP | claimed |
| US-20050155087-A1 | Method of screening compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-07-14 | — | — | US | claimed |
| EP-1463820-A1 | METHOD OF SCREENING COMPOUNDS | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2004-10-06 | — | — | EP | claimed |
| WO-2003052106-A1 | METHOD OF SCREENING COMPOUNDS | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2003-06-26 | — | — | WO | claimed |
| EP-1463820-A4 | METHOD OF SCREENING COMPOUNDS | CHILDRENS MEDICAL CENTER (US) | 2007-09-05 | — | — | EP | disclosed |
| US-20050155087-A1 | Method of screening compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-07-14 | — | — | US | disclosed |
| EP-1463820-A1 | METHOD OF SCREENING COMPOUNDS | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003052106-A1 | METHOD OF SCREENING COMPOUNDS | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2003-06-26 | — | — | WO | disclosed |