Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 14/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5189774 | 0.90 | ALDH1A1 (0.43) | NOS2ALDH1A1KDM4EUSP2GLA | |
| SCHEMBL7057672 | 0.84 | NOS2 (0.42) | NOS2ALDH1A1 | |
| SCHEMBL5192144 | 0.81 | NOS2 (0.48) | NOS2ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL5191690 | 0.79 | NOS2 (0.49) | NOS2ALDH1A1KDM4EKMT2A | |
| SCHEMBL6324458 | 0.78 | NOS2 (0.70) | NOS2 | |
| SCHEMBL5190808 | 0.78 | NOS2 (0.65) | NOS2 | |
| SCHEMBL5193371 | 0.77 | NOS2 (0.66) | NOS2 | |
| SCHEMBL5191424 | 0.77 | ALDH1A1 (0.44) | NOS2ALDH1A1USP2HPGDTSHR | |
| SCHEMBL5211134 | 0.76 | NOS2 (0.65) | NOS2KDM4E | |
| SCHEMBL5195036 | 0.76 | NOS2 (0.54) | NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LAB (US) | 2006-11-15 | — | — | EP | disclosed |