Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.62 |
| ▸ | CA2 | P00918 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | EEF2K | O00418 | 2/20 | 0.50 |
| ▸ | EEF2 | P13639 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | PLK4 | O00444 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | TYK2 | P29597 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | ITK | Q08881 | 1/20 | 0.50 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10325952 | 0.87 | CA1 (0.77) | CA1CA2KMT2AEEF2KEEF2 | |
| SCHEMBL1078732 | 0.85 | CA1 (0.74) | CA1CA2KMT2AEEF2KEEF2 | |
| Water SCHEMBL11782764 | 0.84 | CA1 (0.72) | CA1CA2KMT2AEEF2KEEF2 | |
| Hydrochloric Acid SCHEMBL1877207 | 0.84 | CA1 (0.77) | CA1CA2KMT2AEEF2KEEF2 | |
| Bromide SCHEMBL1044433 | 0.84 | CA1 (0.72) | CA1CA2KMT2AEEF2KEEF2 | |
| SCHEMBL10325611 | 0.83 | CA1 (0.71) | CA1CA2KMT2AEEF2KEEF2 | |
| SCHEMBL1044084 | 0.83 | CA1 (0.71) | CA1CA2KMT2AEEF2KEEF2 | |
| SCHEMBL1044087 | 0.83 | CA1 (0.71) | CA1CA2KMT2AEEF2KEEF2 | |
| Hydrochloric Acid SCHEMBL1179414 | 0.82 | CA1 (0.74) | CA1CA2KMT2AEEF2KEEF2 | |
| Hydrochloric Acid SCHEMBL1179416 | 0.82 | CA1 (0.74) | CA1CA2KMT2AEEF2KEEF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554253-A4 | IMIDAZOLIUM CXCR3 INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2006-09-20 | — | — | EP | disclosed |
| US-20050272936-A1 | Imidazolium cxcr3 inhibitors | SMITHKLINE BEECHAM CORPORATION | 2005-12-08 | — | — | US | disclosed |
| EP-1554253-A1 | IMIDAZOLIUM CXCR3 INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-07-20 | — | — | EP | disclosed |
| WO-2003101970-A1 | IMIDAZOLIUM CXCR3 INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272936-A1 | Imidazolium cxcr3 inhibitors | CXCR3, CXCR1, CCR7 | CA1 2015/4885CA2 976/4885KMT2A 4040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.