Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATP4A | P20648 | 3/20 | 0.36 |
| ▸ | ATP4B | P51164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604950 | 0.85 | KCNMA1 (0.41) | PDE4APDE4BPDE4CPDE4DKCNMA1 | |
| SCHEMBL6837613 | 0.84 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DKCNMA1 | |
| SCHEMBL5722888 | 0.82 | KCNMA1 (0.41) | PDE4APDE4BPDE4CPDE4DKCNMA1 | |
| SCHEMBL6837363 | 0.80 | PKM (0.47) | PDE4APDE4BPDE4CPDE4DKCNMA1 | |
| SCHEMBL5722858 | 0.78 | PKM (0.50) | PDE4APDE4BPDE4CPDE4DKCNMA1 | |
| SCHEMBL5723143 | 0.74 | KCNMA1 (0.48) | PDE4APDE4BPDE4CPDE4DKCNMA1 | |
| SCHEMBL5723120 | 0.71 | KCNMA1 (0.52) | PDE4APDE4BPDE4CPDE4DKCNMA1 | |
| SCHEMBL5722998 | 0.71 | SMN1; SMN2 (0.46) | PDE4APDE4BPDE4CPDE4DKCNMA1 | |
| SCHEMBL6836458 | 0.71 | KCNMA1 (0.56) | PDE4APDE4BPDE4CPDE4DKCNMA1 | |
| SCHEMBL5723108 | 0.70 | NR1H4 (0.33) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771794-B1 | OXYGEN-CONTAINING HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KOGYO KK (JP) | 2006-05-03 | — | — | EP | disclosed |