Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20292600 | 0.83 | MAP3K14 (0.36) | CRBNDDB1MAP3K14TDP1 | |
| SCHEMBL756451 | 0.82 | CRBN (0.38) | CRBNDDB1MAP3K14MEN1APEX1 | |
| SCHEMBL57232 | 0.82 | MAP3K14 (0.39) | CRBNDDB1MAP3K14LMNAMEN1 | |
| SCHEMBL1773976 | 0.79 | CRBN (0.40) | CRBNDDB1MAP3K14MEN1APEX1 | |
| SCHEMBL16049982 | 0.78 | ALDH1A1 (0.39) | LMNAMEN1KMT2A | |
| SCHEMBL1332286 | 0.77 | NPC1 (0.36) | CRBNDDB1MAP3K14LMNAMEN1 | |
| SCHEMBL11095324 | 0.77 | NPC1 (0.36) | CRBNDDB1MAP3K14LMNAMEN1 | |
| SCHEMBL10597719 | 0.77 | MAP3K14 (0.38) | CRBNDDB1MAP3K14 | |
| SCHEMBL2128127 | 0.76 | CRBN (0.35) | CRBNDDB1MAP3K14LMNAMEN1 | |
| SCHEMBL3949247 | 0.76 | MAP3K14 (0.40) | CRBNDDB1MAP3K14LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541328-B2 | Coupling proteins to a modified polysaccharide | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2009-06-02 | — | — | US | disclosed |
| US-20050181985-A1 | Reaction between the terminal aldehyde group and a functional group of the protein; hydroxyalkylstarch-protein conjugate; bioactivity of the proteins is retained; improved solubility of proteins | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2005-08-18 | — | — | US | disclosed |