Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GPX4 | P36969 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57232 | 0.82 | MAP3K14 (0.39) | CRBNDDB1MAP3K14LMNATDP1 | |
| SCHEMBL10597719 | 0.77 | MAP3K14 (0.38) | CRBNDDB1MAP3K14NPC1 | |
| SCHEMBL4396268 | 0.76 | CRBN (0.35) | CRBNDDB1MAP3K14LMNATDP1 | |
| SCHEMBL7264550 | 0.76 | MAP3K14 (0.40) | CRBNDDB1MAP3K14LMNATDP1 | |
| SCHEMBL3949247 | 0.76 | MAP3K14 (0.40) | CRBNDDB1MAP3K14ALDH1A1LMNA | |
| SCHEMBL756451 | 0.75 | CRBN (0.38) | CRBNDDB1MAP3K14ALDH1A1TDP1 | |
| SCHEMBL7530544 | 0.74 | MAP3K14 (0.39) | CRBNDDB1MAP3K14LMNATDP1 | |
| SCHEMBL2782193 | 0.74 | MEN1 (0.40) | CRBNDDB1MAP3K14LMNATDP1 | |
| SCHEMBL7255757 | 0.74 | — | — | |
| SCHEMBL9249468 | 0.74 | MAP3K14 (0.35) | CRBNDDB1MAP3K14TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130177976-A1 | COMBINATION OF CATIONIC POLYMERS AND POLYSACCHARIDES NANOPARTICLES AS A GENE CARRIER | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2013-07-11 | — | — | US | claimed |
| US-20130136714-A1 | FUNCTIONALIZED POLYMER NANOPARTICLES AND THE PHARMACEUTICAL USE THEREOF | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2013-05-30 | — | — | US | claimed |
| EP-1899434-A1 | FLUORESCENT POLYMERS SOLUBLE IN AN AQUEOUS SOLUTION AND A METHOD FOR THE PRODUCTION THEREOF | bioMérieux S.A. (FR) | 2008-03-19 | — | — | EP | claimed |
| WO-2007003781-A1 | FLUORESCENT POLYMERS SOLUBLE IN AN AQUEOUS SOLUTION AND A METHOD FOR THE PRODUCTION THEREOF | BIOMERIEUX S.A. (FR) | 2007-01-11 | — | — | WO | claimed |
| EP-1701741-A2 | COMPLEXES HAVING ADJUVANT ACTIVITY | Polytherics Limited (GB) | 2006-09-20 | — | — | EP | claimed |
| WO-2005065712-A2 | COMPLEXES HAVING ADJUVANT ACTIVITY | POLYTHERICS LIMITED (GB) | 2005-07-21 | — | — | WO | claimed |
| US-20260014186-A1 | POLYMER NANOPARTICLE AND DNA NANOSTRUCTURE COMPOSITIONS AND METHODS FOR NON-VIRAL DELIVERY | BATTELLE MEMORIAL INSTITUTE (US) | 2026-01-15 | — | — | US | disclosed |
| US-12433910-B2 | Polymer nanoparticle and DNA nanostructure compositions and methods for non-viral delivery | BATTELLE MEMORIAL INSTITUTE (US) | 2025-10-07 | — | — | US | disclosed |
| US-20240415865-A1 | POLYMER NANOPARTICLE AND DNA NANOSTRUCTURE COMPOSITIONS AND METHODS FOR NON-VIRAL DELIVERY | BATTELLE MEMORIAL INSTITUTE (US) | 2024-12-19 | — | — | US | disclosed |
| US-12109223-B2 | Polymer nanoparticle and DNA nanostructure compositions and methods for non-viral delivery | BATTELLE MEMORIAL INSTITUTE (US) | 2024-10-08 | — | — | US | disclosed |
| US-12031128-B2 | Rapid design, build, test, and learn technologies for identifying and using non-viral carriers | BATTELLE MEMORIAL INSTITUTE (US) | 2024-07-09 | — | — | US | disclosed |
| US-20240189338-A1 | POLYMER NANOPARTICLE AND DNA NANOSTRUCTURE COMPOSITIONS AND METHODS FOR NON-VIRAL DELIVERY | BATTELLE MEMORIAL INSTITUTE | 2024-06-13 | — | — | US | disclosed |
| US-20240117339-A1 | RAPID DESIGN, BUILD, TEST, AND LEARN TECHNOLOGIES FOR IDENTIFYING AND USING NON-VIRAL CARRIERS | BATTELLE MEMORIAL INSTITUTE | 2024-04-11 | — | — | US | disclosed |
| EP-0644181-B1 | AMINO ACID DERIVATIVE AND USE THEREOF | FUJI PHOTO FILM CO LTD (JP) | 1996-09-04 | — | — | EP | disclosed |
| EP-0644181-A1 | AMINO ACID DERIVATIVE AND USE THEREOF | FUJI PHOTO FILM CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |
| EP-0049860-B1 | PROCESS FOR THE PREPARATION OF REACTIVE THYROID GLAND HORMONES T3 AND T4 DERIVATIVES THAT ARE CAPABLE OF COUPLING, AND THEIR USE | Roche Diagnostics GmbH (DE) | 1984-10-03 | — | — | EP | disclosed |
| US-4423227-A | SILYLATION, ACYLATION | BOEHRINGER MANNHEIM GMBH (DE) | 1983-12-27 | — | — | US | disclosed |
| EP-0049860-A1 | Process for the preparation of reactive thyroid gland hormones T3 and T4 derivatives that are capable of coupling, and their use | Roche Diagnostics GmbH (DE) | 1982-04-21 | — | — | EP | disclosed |
| US-4182695-A | Polyamide-fixed biologically active protein | BOEHRINGER MANNHEIM GMBH (DE) | 1980-01-08 | — | — | US | disclosed |
| US-4119589-A | IMMOBILIZING, IMINOCHLORIDE FORMED BY CHLORINATING DI-SECONDARY AMINE | BOEHRINGER MANNHEIM GMBH (DE) | 1978-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12031128-B2 | Rapid design, build, test, and learn technologies for identifying and using non-viral carriers | PHAX, POLRMT, RFTN1 | CRBN 1489/4885DDB1 543/4885MAP3K14 2430/4885 |
| US-12109223-B2 | Polymer nanoparticle and DNA nanostructure compositions and methods for non-viral delivery | POLN, POLRMT, MAVS | CRBN 1619/4885DDB1 275/4885MAP3K14 4050/4885 |
| US-12433910-B2 | Polymer nanoparticle and DNA nanostructure compositions and methods for non-viral delivery | POLN, POLRMT, MAVS | CRBN 1619/4885DDB1 275/4885MAP3K14 4050/4885 |
| US-20240117339-A1 | RAPID DESIGN, BUILD, TEST, AND LEARN TECHNOLOGIES FOR IDENTIFYING AND USING NON-VIRAL CARRIERS | PHAX, POLRMT, RFTN1 | CRBN 1489/4885DDB1 543/4885MAP3K14 2430/4885 |
| US-20240415865-A1 | POLYMER NANOPARTICLE AND DNA NANOSTRUCTURE COMPOSITIONS AND METHODS FOR NON-VIRAL DELIVERY | POLN, POLRMT, MAVS | CRBN 1619/4885DDB1 275/4885MAP3K14 4050/4885 |
| US-20240189338-A1 | POLYMER NANOPARTICLE AND DNA NANOSTRUCTURE COMPOSITIONS AND METHODS FOR NON-VIRAL DELIVERY | POLN, POLRMT, MAVS | CRBN 1619/4885DDB1 275/4885MAP3K14 4050/4885 |
| US-20260014186-A1 | POLYMER NANOPARTICLE AND DNA NANOSTRUCTURE COMPOSITIONS AND METHODS FOR NON-VIRAL DELIVERY | POLRMT, FUS, POLM | CRBN 2545/4885DDB1 250/4885MAP3K14 4137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.