Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 0.76 |
| ▸ | ACHE | P22303 | 4/20 | 0.69 |
| ▸ | RAD52 | P43351 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3571208 | 0.86 | HRH3 (1.00) | HRH3ACHERAD52 | |
| SCHEMBL28619817 | 0.85 | SIGMAR1 (0.62) | HRH3 | |
| SCHEMBL3567760 | 0.82 | HRH3 (1.00) | HRH3ACHERAD52 | |
| Jnj-5207852 SCHEMBL3577334 | 0.82 | HRH3 (1.00) | HRH3ACHERAD52 | |
| SCHEMBL3580340 | 0.82 | HRH3 (1.00) | HRH3ACHERAD52 | |
| SCHEMBL3572587 | 0.82 | HRH3 (1.00) | HRH3ACHERAD52 | |
| SCHEMBL5770194 | 0.81 | HRH3 (0.75) | HRH3 | |
| SCHEMBL5709502 | 0.79 | SIGMAR1 (0.60) | HRH3 | |
| SCHEMBL3580326 | 0.78 | HRH3 (1.00) | HRH3ACHERAD52 | |
| SCHEMBL4094667 | 0.78 | HRH3 (1.00) | HRH3ACHERAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313721-B1 | NON-IMIDAZOLE ARYLOXYALKYLAMINES AS H3 RECEPTOR LIGANDS | ORTHO MCNEIL PHARM INC (US) | 2006-03-08 | — | — | EP | claimed |