Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28619817 | 0.94 | SIGMAR1 (0.62) | SIGMAR1HRH3MEN1KMT2ADRD3 | |
| SCHEMBL5709501 | 0.88 | LTA4H (0.55) | MEN1KMT2AKCNA5DRD3DRD2 | |
| SCHEMBL28619862 | 0.84 | LTA4H (0.70) | SIGMAR1HRH3MEN1KMT2AALDH1A1 | |
| SCHEMBL5709457 | 0.84 | SIGMAR1 (0.60) | SIGMAR1HRH3MEN1KMT2AALDH1A1 | |
| SCHEMBL2324373 | 0.83 | MCHR1 (0.80) | MCHR1 | |
| SCHEMBL28632356 | 0.81 | SIGMAR1 (0.56) | SIGMAR1HRH3MEN1KMT2AALDH1A1 | |
| SCHEMBL28511016 | 0.81 | DRD4 (0.59) | MEN1KMT2ADRD3DRD2 | |
| SCHEMBL5723567 | 0.79 | HRH3 (0.76) | HRH3 | |
| SCHEMBL28513178 | 0.78 | ATF4 (0.59) | SIGMAR1HRH3ALDH1A1DRD3DRD2 | |
| SCHEMBL5709509 | 0.77 | SIGMAR1 (0.54) | SIGMAR1HRH3MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005089759-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |