SCHEMBL5723916

SCHEMBL5723916

CC(C)(C)[Si](C)(C)OCC(CO[Si](C)(C)C(C)(C)C)NC(=O)c1csc(N2CC(OS(C)(=O)=O)C2)n1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OGA O60502 3/20 0.35
ALPL P05186 2/20 0.33
ALPI P09923 2/20 0.33
ALPG P10696 2/20 0.33
ACACB O00763 2/20 0.33
HRH3 Q9Y5N1 2/20 0.32
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5724193 0.96 OGA (0.34) OGAALPLALPIALPGACACB
SCHEMBL5724500 0.94 CNR2 (0.35) OGAALPLALPIALPGACACB
SCHEMBL5723671 0.92 OGA (0.36) OGAALPLALPIALPGACACB
SCHEMBL5723674 0.92 OGA (0.36) OGAALPLALPIALPGACACB
SCHEMBL5723888 0.90 OGA (0.35) OGAALPLALPIALPGACACB
SCHEMBL5724487 0.89 OGA (0.38) OGAALPLALPIALPGACACB
SCHEMBL5724148 0.88 OGA (0.34) OGAALPLALPIALPGACACB
SCHEMBL5723932 0.85 OGA (0.31) OGAALPLALPIALPG
SCHEMBL5724099 0.84 OGA (0.32) OGAALPLALPIALPG
SCHEMBL5723874 0.84 OGA (0.36) OGAALPLALPIALPGACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1340757-B1 1-METHYLCARBAPENEM DERIVATIVES SANKYO CO (JP) 2006-10-11 EP disclosed
US-7001897-B2 1-methylcarbapenem derivatives SANKYO COMPANY, LIMITED (JP) 2006-02-21 US disclosed
US-20040014962-A1 1-Methylcarbapenem derivatives SANKYO COMPANY, LIMITED (JP) 2004-01-22 US disclosed
EP-1340757-A1 1-METHYLCARBAPENEM DERIVATIVES Sankyo Company, Limited (JP) 2003-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040014962-A1 1-Methylcarbapenem derivatives CD14, CPT1A, ACMSD OGA 3469/4885ALPL 1131/4885ALPI 204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.