SCHEMBL5724191

SCHEMBL5724191

O=C(NC(CO)CO)c1csc(N2CC(O)C2)n1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OGA O60502 3/20 0.37
L3MBTL1 Q9Y468 1/20 0.34
PIN1 Q13526 2/20 0.34
ACKR3 P25106 2/20 0.34
CHEK1 O14757 1/20 0.34
CNR2 P34972 1/20 0.34
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5723737 0.93 POLB (0.37) OGACNR2
SCHEMBL5724431 0.91 CNR2 (0.45) OGAACKR3CNR2
SCHEMBL5724433 0.91 CNR2 (0.45) OGAACKR3CNR2
SCHEMBL5724564 0.88 OGA (0.40) OGAPIN1ACKR3CNR2KMT2A
SCHEMBL5724565 0.88 OGA (0.40) OGAPIN1ACKR3CNR2KMT2A
SCHEMBL5724290 0.85 CNR1 (0.40) OGACNR2
SCHEMBL5724286 0.85 CNR1 (0.40) OGACNR2
SCHEMBL5724178 0.84 OGA (0.50) OGAPIN1ACKR3CNR2
SCHEMBL5724028 0.83 OGA (0.42) OGAL3MBTL1ACKR3CNR2
SCHEMBL5724527 0.83 OGA (0.38) OGAPIN1ACKR3CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1340757-B1 1-METHYLCARBAPENEM DERIVATIVES SANKYO CO (JP) 2006-10-11 EP disclosed
US-7001897-B2 1-methylcarbapenem derivatives SANKYO COMPANY, LIMITED (JP) 2006-02-21 US disclosed
US-20040014962-A1 1-Methylcarbapenem derivatives SANKYO COMPANY, LIMITED (JP) 2004-01-22 US disclosed
EP-1340757-A1 1-METHYLCARBAPENEM DERIVATIVES Sankyo Company, Limited (JP) 2003-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040014962-A1 1-Methylcarbapenem derivatives CD14, CPT1A, ACMSD OGA 3469/4885L3MBTL1 318/4885PIN1 3860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.