SCHEMBL5724320

SCHEMBL5724320

CS(=O)(=O)OC1CN(c2nc(C(=O)NC3CCCC3)cs2)C1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
OGA O60502 1/20 0.46
TYR P14679 1/20 0.43
ACKR3 P25106 2/20 0.42
DNM1L O00429 2/20 0.40
HSD11B1 P28845 1/20 0.38
ALDH1A1 P00352 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37
KMT2A Q03164 1/20 0.37
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SMYD3 Q9H7B4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5724022 0.99 OGA (0.47) OGATYRACKR3DNM1LHSD11B1
SCHEMBL5724092 0.98 OGA (0.44) OGATYRACKR3DNM1LHSD11B1
SCHEMBL5723946 0.96 ACKR3 (0.43) OGATYRACKR3DNM1LHSD11B1
SCHEMBL5723964 0.85 OGA (0.46) OGAHRH3
SCHEMBL5724259 0.85 OGA (0.41) OGAACKR3HRH3NPC1RAB9A
SCHEMBL5724459 0.84 OGA (0.49) OGATYRACKR3DNM1LHSD11B1
SCHEMBL5724054 0.83 TYR (0.51) OGATYRACKR3DNM1LHSD11B1
SCHEMBL5723880 0.82 PARP1 (0.39) OGAACKR3HRH3
SCHEMBL5724061 0.81 OGA (0.47) OGATYRACKR3DNM1LHSD11B1
SCHEMBL5723657 0.80 HRH3 (0.47) OGAALDH1A1HRH3KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1340757-B1 1-METHYLCARBAPENEM DERIVATIVES SANKYO CO (JP) 2006-10-11 EP disclosed
US-7001897-B2 1-methylcarbapenem derivatives SANKYO COMPANY, LIMITED (JP) 2006-02-21 US disclosed
US-20040014962-A1 1-Methylcarbapenem derivatives SANKYO COMPANY, LIMITED (JP) 2004-01-22 US disclosed
EP-1340757-A1 1-METHYLCARBAPENEM DERIVATIVES Sankyo Company, Limited (JP) 2003-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040014962-A1 1-Methylcarbapenem derivatives CD14, CPT1A, ACMSD OGA 3469/4885TYR 2189/4885ACKR3 4262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.