Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.61 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3461758 | 0.86 | CD38 (0.46) | HPGDMEN1KMT2AMAPTHIF1A | |
| SCHEMBL5723905 | 0.82 | HSPA5 (0.61) | HPGDMAPTHIF1ASMN1; SMN2HSPA5 | |
| SCHEMBL5212271 | 0.81 | HSP90AA1 (0.60) | HPGDKMT2AMAPTHIF1ACYP3A4 | |
| SCHEMBL3460044 | 0.81 | L3MBTL1 (0.46) | HPGDMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL825001 | 0.80 | MEN1 (0.80) | HPGDMEN1KMT2AMAPTHIF1A | |
| SCHEMBL7134588 | 0.80 | TSHR (0.54) | HPGDMEN1KMT2AMAPTHIF1A | |
| Dichlorophen SCHEMBL16619827 | 0.78 | CYP3A4 (0.91) | HPGDMEN1KMT2AMAPTHIF1A | |
| Dichlorophen SCHEMBL18052 | 0.78 | CYP3A4 (1.00) | HPGDMEN1KMT2AMAPTHIF1A | |
| Dichlorophen SCHEMBL9109126 | 0.78 | CYP3A4 (1.00) | HPGDMEN1KMT2AMAPTHIF1A | |
| Dichlorophen SCHEMBL29524636 | 0.78 | CYP3A4 (1.00) | HPGDMEN1KMT2AMAPTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633715-A1 | 2-(6-AMINO-PYRIDIN-3-YL)-2-HYDROXYETHYLAMINE DERIVATIVES AS BETA 2-ADRENOCEPTORS AGONISTS | Pfizer Limited (GB) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004108676-A1 | 2-(6-AMINO-PYRIDIN-3-YL)-2-HYDROXYETHYLAMINE DERIVATIVES AS BETA 2-ADRENOCEPTORS AGONISTS | PFIZER LIMITED (GB) | 2004-12-16 | — | — | WO | disclosed |