Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TRPC3 | Q13507 | 5/20 | 0.34 |
| ▸ | TRPC6 | Q9Y210 | 5/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5723784 | 0.91 | KMT2A (0.40) | HPGDRAB9ATRPC3TRPC6HRH3 | |
| SCHEMBL5724610 | 0.91 | KMT2A (0.39) | HPGDRAB9ATRPC3TRPC6HRH3 | |
| SCHEMBL5724499 | 0.89 | KMT2A (0.42) | HPGDRAB9ATRPC3TRPC6HRH3 | |
| SCHEMBL5724062 | 0.88 | TSHR (0.41) | HPGDRAB9ATRPC3TRPC6HRH3 | |
| SCHEMBL5723626 | 0.87 | HTR2C (0.46) | RAB9AHRH3 | |
| SCHEMBL5724468 | 0.83 | HRH3 (0.37) | TRPC3TRPC6HRH3KMT2AGFER | |
| SCHEMBL5723948 | 0.83 | HTR2C (0.40) | HPGDRAB9ACNR2TRPC3TRPC6 | |
| SCHEMBL5724059 | 0.80 | HRH3 (0.44) | RAB9AHRH3KMT2A | |
| SCHEMBL5724125 | 0.78 | OGA (0.42) | HPGDRAB9AHRH3KMT2A | |
| SCHEMBL5724215 | 0.78 | OGA (0.42) | HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1340757-B1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO CO (JP) | 2006-10-11 | — | — | EP | disclosed |
| US-7001897-B2 | 1-methylcarbapenem derivatives | SANKYO COMPANY, LIMITED (JP) | 2006-02-21 | — | — | US | disclosed |
| US-20040014962-A1 | 1-Methylcarbapenem derivatives | SANKYO COMPANY, LIMITED (JP) | 2004-01-22 | — | — | US | disclosed |
| EP-1340757-A1 | 1-METHYLCARBAPENEM DERIVATIVES | Sankyo Company, Limited (JP) | 2003-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014962-A1 | 1-Methylcarbapenem derivatives | CD14, CPT1A, ACMSD | HPGD 1268/4885RAB9A 3028/4885CNR2 1743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.