SCHEMBL5724432

SCHEMBL5724432

CC(C)C[C@H](NC(=O)c1csc(N2CC(O)C2)n1)C(O[SiH](C)C)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.36
OGA O60502 3/20 0.35
ABCB1 P08183 2/20 0.34
HRH3 Q9Y5N1 2/20 0.32
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
ACACB O00763 1/20 0.31
KMT2A Q03164 1/20 0.30
ALPL P05186 1/20 0.30
ALPI P09923 1/20 0.30
ALPG P10696 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5724427 1.00 CNR2 (0.36) CNR2OGAABCB1HRH3ALDH1A1
SCHEMBL5723866 0.91 OGA (0.34) CNR2OGAABCB1HRH3ALDH1A1
SCHEMBL5724503 0.90 OGA (0.33) OGAABCB1HRH3ACACBALPL
SCHEMBL5724497 0.90 OGA (0.33) OGAABCB1HRH3ACACBALPL
SCHEMBL5724238 0.89 ABCB1 (0.33) OGAABCB1ACACBKMT2A
SCHEMBL5724114 0.87 OGA (0.37) CNR2OGAABCB1HRH3ACACB
SCHEMBL5724101 0.87 OGA (0.37) CNR2OGAABCB1HRH3ACACB
SCHEMBL5724495 0.86 OGA (0.33) OGAKMT2AALPLALPIALPG
SCHEMBL5826396 0.85 OGA (0.35) CNR2OGAABCB1HRH3ACACB
SCHEMBL5724187 0.81 ACACB (0.33) OGAABCB1HRH3ACACBALPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1340757-B1 1-METHYLCARBAPENEM DERIVATIVES SANKYO CO (JP) 2006-10-11 EP disclosed
US-7001897-B2 1-methylcarbapenem derivatives SANKYO COMPANY, LIMITED (JP) 2006-02-21 US disclosed
US-20040014962-A1 1-Methylcarbapenem derivatives SANKYO COMPANY, LIMITED (JP) 2004-01-22 US disclosed
EP-1340757-A1 1-METHYLCARBAPENEM DERIVATIVES Sankyo Company, Limited (JP) 2003-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040014962-A1 1-Methylcarbapenem derivatives CD14, CPT1A, ACMSD CNR2 1743/4885OGA 3469/4885ABCB1 268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.