Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.61 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.44 |
| ▸ | IP6K1 | Q92551 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | S100B | P04271 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 4/20 | 0.43 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29360110 | 0.80 | HTR3E (0.49) | TERTMAPTHTTTP53THRB | |
| Iodide SCHEMBL30950746 | 0.78 | GAA (0.49) | ALDH1A1MAPTMEN1GAAHTT | |
| Iodide SCHEMBL12830327 | 0.77 | TERT (0.42) | TERTPDE3BPDE3AALDH1A1MAPT | |
| SCHEMBL13386405 | 0.76 | PRKDC (0.45) | TERTPDE3BPDE3AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL13386450 | 0.75 | PRKDC (0.44) | TERTPDE3BPDE3AALDH1A1MAPT | |
| SCHEMBL21279431 | 0.70 | GAA (0.69) | TERTMAP4K4IP6K1ALDH1A1MAPT | |
| SCHEMBL18493222 | 0.69 | TERT (0.92) | TERTMAP4K4PDE3BPDE3AIP6K1 | |
| SCHEMBL27517099 | 0.69 | TERT (0.58) | TERTMAP4K4PDE3BPDE3AIP6K1 | |
| SCHEMBL28387400 | 0.69 | TERT (0.62) | TERTMAP4K4PDE3BPDE3AIP6K1 | |
| SCHEMBL31218421 | 0.69 | TERT (0.62) | TERTMAP4K4PDE3BPDE3AIP6K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687286-A1 | DEVELOPMENTS IN BIOLOGICALLY ACTIVE METHYLENE BLUE DERIVATIVES (2) | Photopharmica Limited (GB) | 2006-08-09 | — | — | EP | claimed |
| WO-2005054217-A1 | DEVELOPMENTS IN BIOLOGICALLY ACTIVE METHYLENE BLUE DERIVATIVES (2) | PHOTOPHARMICA LIMITED (GB) | 2005-06-16 | — | — | WO | claimed |
| EP-1687286-A1 | DEVELOPMENTS IN BIOLOGICALLY ACTIVE METHYLENE BLUE DERIVATIVES (2) | Photopharmica Limited (GB) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005054217-A1 | DEVELOPMENTS IN BIOLOGICALLY ACTIVE METHYLENE BLUE DERIVATIVES (2) | PHOTOPHARMICA LIMITED (GB) | 2005-06-16 | — | — | WO | disclosed |