Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 4/20 | 0.76 |
| ▸ | MAOB | P27338 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 3/20 | 0.57 |
| ▸ | MAOA | P21397 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5724935 | 0.93 | MIF (0.76) | MIFMAOBMEN1KMT2ATDP1 | |
| SCHEMBL29837280 | 0.87 | MIF (1.00) | MIFMAOBMEN1KMT2ATDP1 | |
| Sappanone A SCHEMBL29651769 | 0.85 | MIF (0.80) | MIFMAOBMEN1KMT2ATDP1 | |
| Sappanone A SCHEMBL2521583 | 0.85 | MIF (0.80) | MIFMAOBMEN1KMT2ATDP1 | |
| SCHEMBL8461421 | 0.84 | MIF (0.67) | MIFMAOBMEN1KMT2ATDP1 | |
| SCHEMBL8461418 | 0.84 | MIF (0.67) | MIFMAOBMEN1KMT2ATDP1 | |
| SCHEMBL6965941 | 0.81 | MAOA (0.71) | MAOBMEN1KMT2AMAOAMAPT | |
| SCHEMBL5726073 | 0.80 | MAOB (0.72) | MIFMAOBMEN1KMT2ATDP1 | |
| SCHEMBL5725497 | 0.80 | MAPT (0.77) | MIFMAOBMEN1KMT2ATDP1 | |
| Isobonducellin SCHEMBL31238399 | 0.79 | MAOB (1.00) | MIFMAOBMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080781-A | Tetralone or benzopyranone derivatives and a method for producing them | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 2000-06-27 | — | — | US | claimed |
| EP-0902003-B1 | NOVEL TETRALONE OR BENZOPYRANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | DAIICHI SEIYAKU CO (JP) | 2006-07-26 | — | — | EP | disclosed |
| US-6080781-A | Tetralone or benzopyranone derivatives and a method for producing them | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 2000-06-27 | — | — | US | disclosed |
| EP-0902003-A1 | NOVEL TETRALONE OR BENZOPYRANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 1999-03-17 | — | — | EP | disclosed |