SCHEMBL572533

SCHEMBL572533

COc1cc2nc(-c3ccc(C(=O)NN)cc3)sc2cc1OC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.55
RAB9A P51151 7/20 0.55
KDM4E B2RXH2 6/20 0.55
PPARG P37231 1/20 0.55
NR2E3 Q9Y5X4 1/20 0.55
NCOR2 Q9Y618 1/20 0.55
HDAC6 Q9UBN7 5/20 0.55
SMN1; SMN2 Q16637 5/20 0.54
NPC1 O15118 4/20 0.54
KMT2A Q03164 3/20 0.54
TP53 P04637 3/20 0.50
GAA P10253 3/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
HDAC3 O15379 3/20 0.49
HDAC1 Q13547 3/20 0.49
HDAC2 Q92769 3/20 0.49
HDAC8 Q9BY41 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6946336 0.86 KDM4E (0.59) MAPTRAB9AKDM4EPPARGNR2E3
SCHEMBL8346414 0.86 SMN1; SMN2 (0.47) MAPTRAB9AKDM4EPPARGNR2E3
SCHEMBL13806230 0.76 AHR (0.68)
SCHEMBL11335745 0.76 MAPT (0.51) MAPTRAB9AKDM4EPPARGNR2E3
SCHEMBL1608797 0.74 ILK (0.53) MAPTRAB9AKDM4EPPARGSMN1; SMN2
SCHEMBL7053654 0.72 SMN1; SMN2 (0.56) MAPTRAB9AKDM4EPPARGNR2E3
SCHEMBL21376599 0.72 SCD (0.64) MAPTRAB9AKDM4ESMN1; SMN2NPC1
SCHEMBL11750870 0.71 APP (0.64) MAPTRAB9AKDM4ESMN1; SMN2NPC1
SCHEMBL9435301 0.71 KDM4E (0.57) MAPTRAB9AKDM4EPPARGNR2E3
SCHEMBL9797066 0.71 KDM4E (0.71) MAPTRAB9AKDM4EHDAC6SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2601048-A2 COMPOSITIONS AND METHODS FOR DETECTION OF SOILS ON FABRICS The Sun Products Corporation (US) 2013-06-12 EP disclosed
US-20120196375-A1 Compositions and Methods for Detection of Soils on Fabrics THE SUN PRODUCTS CORPORATION (US) 2012-08-02 US disclosed
WO-2012019030-A2 COMPOSITIONS AND METHODS FOR DETECTION OF SOILS ON FABRICS THE SUN PRODUCTS CORPORATION (US) 2012-02-09 WO disclosed
US-7981686-B2 Indicator for assessing body odor, process for producing the same, body odor assessment method, method of assessing efficaciousness of deodorant and kit for conveniently assessing body odor KAO CORPORATION (JP) 2011-07-19 US disclosed
US-20100184122-A1 INDICATOR FOR ASSESSING BODY ODOR, PROCESS FOR PRODUCING THE SAME, BODY ODOR ASSESSMENT METHOD, METHOD OF ASSESSING EFFICACIOUSNESS OF DEODORANT AND KIT FOR CONVENIENTLY ASSESSING BODY ODOR KAO CORPORATION (JP) 2010-07-22 US disclosed
US-20060160240-A1 Indicator for assessing body odor, process for producing the same, body odor assessment method, method of assessing efficaciousness of deodorant and kit for conveniently assessing body odor KAO CORPORATION (JP) 2006-07-20 US disclosed
EP-1553411-A1 INDICATOR FOR ASSESSING BODY ODOR, PROCESS FOR PRODUCING THE SAME, BODY ODOR ASSESSMENT METHOD, METHOD OF ASSESSING EFFICACIOUSNESS OF DEODORANT AND KIT FOR CONVENIENTLY ASSESING BODY ODOR Kao Corporation (JP) 2005-07-13 EP disclosed
US-5790627-A Method and apparatus for observing a specimen using an X-ray microscope RESEARCH DEVELOPMENT CORP. (JP) 1998-08-04 US disclosed