SCHEMBL572684

SCHEMBL572684

O=C(O)C1CC2CCN1CC2

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ACE P12821 5/20 0.36
ALDH1A1 P00352 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5473763 0.98 ACE (0.35) ACEALDH1A1SMN1; SMN2ATM
Hydrochloric Acid SCHEMBL14343221 0.98 ACE (0.35) ACEALDH1A1SMN1; SMN2ATM
Hydrochloric Acid SCHEMBL14343353 0.98 ACE (0.35) ACEALDH1A1SMN1; SMN2ATM
Bromide SCHEMBL28148076 0.98 ACE (0.35) ACEALDH1A1SMN1; SMN2ATM
SCHEMBL2428126 0.86 ATM (0.35) ACEALDH1A1SMN1; SMN2ATM
SCHEMBL901345 0.86 ATM (0.35) ACEALDH1A1SMN1; SMN2ATM
SCHEMBL7719910 0.80 GAA (0.30)
SCHEMBL30363259 0.78 GAA (0.33)
SCHEMBL5433240 0.78 SMN1; SMN2 (0.33) SMN1; SMN2
Hydrochloric Acid SCHEMBL6990898 0.78 GAA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111398497-B Application of kynurenine in identifying Chinese bee honey and apis mellifera honey 中国农业科学院蜜蜂研究所 2022-08-19 CN claimed
US-6180739-B1 CYCLODEXTRINS WITH ACRYLATE AND ANHYDRIDES AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION 2001-01-30 US claimed
EP-0813544-A4 1998-01-07 EP claimed
EP-0813544-A1 BRADYKININ ANTAGONIST PEPTIDES INCORPORATING N-SUBSTITUTED GLYCINES CORTECH, INC. (US) 1997-12-29 EP claimed
WO-1995024422-A1 BRADYKININ ANTAGONIST PEPTIDES INCORPORATING N-SUBSTITUTED GLYCINES CORTECH, INC. (US) 1995-09-14 WO claimed
US-5401783-A Adhesion-promoting agents incorporating polyvalent cations AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1995-03-28 US claimed
US-5270351-A Adhesion-promoting agents incorporating polyvalent cations AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1993-12-14 US claimed
CN-115894447-B METTL3 inhibitors and uses thereof 成都先导药物开发股份有限公司 2024-10-01 CN disclosed
WO-2024153180-A1 HETEROCYCLIC COMPOUND, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 上海艾力斯医药科技股份有限公司 2024-07-25 WO disclosed
CN-117865988-A Tetrafused ring compound, preparation method and application thereof 厦门宝太生物科技股份有限公司 2024-04-12 CN disclosed
CN-111989331-B Synthesis method of 2- [ (2S) -1-azabicyclo [2.2.2] oct-2-yl ] -6- (3-methyl-1H-pyrazol-4-yl) thieno [3,2-d ] pyrimidine-4 (3H) -ketone 武田药品工业株式会社 2024-04-12 CN disclosed
CN-117736182-A MetTL3 inhibitors and uses thereof 成都先导药物开发股份有限公司 2024-03-22 CN disclosed
US-20240084343-A1 METHODS OF USING NATURAL AND ENGINEERED ORGANISMS TO PRODUCE SMALL MOLECULES FOR INDUSTRIAL APPLICATION KIVERDI INC (US) 2024-03-14 US disclosed
EP-0623589-A1 Coupling reagent and method for coupling amines with carboxylic acids PFIZER INC. (US) 1994-11-09 EP disclosed
WO-1994017036-A1 S-LIPOPHILIC ALIPHATIC CARBONYL [N-MERCAPTOACYL-(AMINO ACID OR PEPTIDE)] COMPOUNDS AS ANTIHYPERTENSIVE AGENTS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 1994-08-04 WO disclosed
US-5320886-A Hydrophilic crosslinking monomers and polymers made therefrom AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1994-06-14 US disclosed
US-5270351-A Adhesion-promoting agents incorporating polyvalent cations AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1993-12-14 US disclosed
EP-0473442-A1 A substituted pyrazine and its salts, compositions containing them and their use in medicine MERCK SHARP & DOHME LTD. (GB) 1992-03-04 EP disclosed
US-4146628-A NO SIDE EFFECTS OPPENHEIMER EDNA 1979-03-27 US disclosed
US-4146628-A NO SIDE EFFECTS OPPENHEIMER EDNA 1979-03-27 US disclosed