Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | AQP1 | P29972 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL572715 | 1.00 | ALDH1A1 (0.39) | ALDH1A1KDM4EUSP2CA2LMNA | |
| SCHEMBL10224224 | 1.00 | ALDH1A1 (0.39) | ALDH1A1KDM4EUSP2CA2LMNA | |
| SCHEMBL572943 | 0.99 | LMNA (0.39) | ALDH1A1KDM4EUSP2CA2LMNA | |
| SCHEMBL572944 | 0.99 | LMNA (0.39) | ALDH1A1KDM4EUSP2CA2LMNA | |
| SCHEMBL10224228 | 0.99 | LMNA (0.39) | ALDH1A1KDM4EUSP2CA2LMNA | |
| SCHEMBL574196 | 0.97 | ALDH1A1 (0.40) | ALDH1A1KDM4EUSP2CA2LMNA | |
| SCHEMBL574197 | 0.97 | ALDH1A1 (0.40) | ALDH1A1KDM4EUSP2CA2LMNA | |
| SCHEMBL573814 | 0.94 | LMNA (0.39) | ALDH1A1KDM4EUSP2CA2LMNA | |
| SCHEMBL573815 | 0.94 | LMNA (0.39) | ALDH1A1KDM4EUSP2CA2LMNA | |
| SCHEMBL574057 | 0.92 | LPAR1 (0.39) | ALDH1A1KDM4EUSP2CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598478-A2 | ARYLSULFONAMIDE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE | Neurotherapeutics Pharma, Inc. (US) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012018635-A2 | ARYLSULFONAMIDE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE | NEUROTHERAPEUTICS PHARMA, INC. (US) | 2012-02-09 | — | — | WO | disclosed |