Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | CNR2 | P34972 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | MPI | P34949 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | SELL | P14151 | 1/20 | 0.46 |
| ▸ | SELP | P16109 | 1/20 | 0.46 |
| ▸ | SELE | P16581 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31496789 | 1.00 | ACHE (0.52) | ACHECNR2ALDH1A1KDM4EMAPT | |
| SCHEMBL10053939 | 0.83 | SELL (0.62) | ACHEALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL10053940 | 0.81 | ACHE (0.59) | ACHECNR2ALDH1A1KDM4EMAPT | |
| SCHEMBL29421895 | 0.79 | ACHE (0.70) | ACHEALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL1427958 | 0.79 | ACHE (0.70) | ACHEALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL27408145 | 0.77 | EP300 (0.48) | ACHEALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL10935658 | 0.77 | ACHE (0.48) | ACHEALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL3623027 | 0.77 | ACHE (0.48) | ACHECNR2ALDH1A1KDM4EMAPT | |
| SCHEMBL562147 | 0.77 | ERN1 (0.63) | ACHEALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL29888627 | 0.76 | CYP3A4 (0.57) | ACHEALDH1A1KDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289855-A1 | METHOD FOR PREPARING PHOSPHORUS-CONTAINING LIGAND | Zhejiang NHU Company Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |
| WO-2023206791-A1 | METHOD FOR PREPARING PHOSPHORUS-CONTAINING LIGAND | 浙江新和成股份有限公司 | 2023-11-02 | — | — | WO | disclosed |
| EP-1214290-B1 | MULTIDENTATE PHOSPHITE LIGANDS, CATALYTIC COMPOSITIONS CONTAINING THEM AND THEIR USE IN HYDROCYANATION REACTIONS | INVISTA TECH SARL (US) | 2006-11-02 | — | — | EP | disclosed |
| EP-1000022-B1 | HYDROCYANATION PROCESSES AND MULTIDENTATE PHOSPHITE LIGAND AND NICKEL CATALYST COMPOSITIONS THEREFOR | INVISTA TECH SARL (US) | 2005-03-30 | — | — | EP | disclosed |
| EP-1214282-B1 | HYDROFORMYLATION PROCESS UTILIZING MULTIDENTATE PHOSPHITE LIGANDS | INVISTA TECH SARL (US) | 2005-02-23 | — | — | EP | disclosed |
| US-6812352-B2 | REACTING AN ACYCLIC, ALIPHATIC, MONOETHYLENICALLY UNSATURATED COMPOUND WITH A SOURCE OF HCN IN THE PRESENCE OF A CATALYST PRECURSOR COMPOSITION COMPRISING A LEWIS ACID, A ZERO-VALENT NICKEL, AND A MULTIDENTATE PHOSPHITE LIGAND FOR HYDROCYANATION | INVISTA NORTH AMERICA S.A.R.L. | 2004-11-02 | — | — | US | disclosed |
| US-6515161-B1 | Multidentate phosphite ligands in a catalyst composition. In particular, the ligands have heteroatom-containing substituents on the carbon attached to the ortho position of the terminal phenol group. | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-02-04 | — | — | US | disclosed |
| US-20030023110-A1 | Multidentate phosphite ligands, catalytic compositions containing such ligands, and catalytic prosses utilizing such catalytic compositions | INVISTA NORTH AMERICA S.A.R.L. | 2003-01-30 | — | — | US | disclosed |
| EP-1214290-A1 | MULTIDENTATE PHOSPHITE LIGANDS AND CATALYTIC COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001021580-A1 | MULTIDENTATE PHOSPHITE LIGANDS, CATALYTIC COMPOSITIONS CONTAINING SUCH LIGANDS AND CATALYTIC PROCESSES UTILIZING SUCH CATALYTIC COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-03-29 | — | — | WO | disclosed |
| US-6171996-B1 | Hydrocyanation processes and multidentate phosphite ligand and nickel catalyst compositions therefor | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-01-09 | — | — | US | disclosed |
| US-6127567-A | HYDROCYANATION OF AN ALIPHATIC MONOETHYLENICALLY UNSATURATED COMPOUND, USING A CATALYST PRECURSOR COMPOSITION OF ZERO-VALENT NICKEL, A LEWIS ACID, AND A MULTIDENTATE PHOSPHITE LIGAND OF GIVEN FORMULA; CATALYST SELECTIVITY | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-10-03 | — | — | US | disclosed |
| US-6069267-A | REACTING AT BETWEEN ABOUT-25 AND 10 DEGREE C., PHOSPHORUS TRICHLORIDE AND AN ARYL ALCOHOL TO PRODUCE A DIARYLPHOSPHORUS CHLORIDE AND HYDROGEN CHLORIDE FORMING AN INSOLUBLE SALT WITH A BASE AND IS REMOVED; REACT WITH A DIHYDRIC ARYL COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-05-30 | — | — | US | disclosed |
| EP-1000022-A1 | HYDROCYANATION PROCESSES AND MULTIDENTATE PHOSPHITE LIGAND AND NICKEL CATALYST COMPOSITIONS THEREFOR | E.I. DU PONT DE NEMOURS & COMPANY INCORPORATED (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999006358-A1 | HYDROCYANATION PROCESSES AND MULTIDENTATE PHOSPHITE LIGAND AND NICKEL CATALYST COMPOSITIONS THEREFOR | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030023110-A1 | Multidentate phosphite ligands, catalytic compositions containing such ligands, and catalytic prosses utilizing such catalytic compositions | PGM2, PAPSS1, PMM2 | ACHE 267/4885CNR2 3401/4885ALDH1A1 4101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.