Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 4/20 | 0.59 |
| ▸ | GSK3B | P49841 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | POLB | P06746 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.55 |
| ▸ | RECQL | P46063 | 4/20 | 0.55 |
| ▸ | THRB | P10828 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | APEX1 | P27695 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23009248 | 0.75 | KDM4E (0.63) | MEN1KMT2AMAPTPOLBTDP1 | |
| SCHEMBL11157478 | 0.75 | MAPT (0.61) | MEN1KMT2AMAPTPOLBTDP1 | |
| SCHEMBL6734762 | 0.74 | GSK3A (0.60) | GSK3AGSK3BMEN1KMT2AMAPT | |
| SCHEMBL9069344 | 0.73 | GSK3A (0.63) | GSK3AGSK3BMEN1KMT2AMAPT | |
| SCHEMBL31411564 | 0.71 | POLB (0.47) | MEN1KMT2AMAPTPOLBTDP1 | |
| SCHEMBL31411521 | 0.71 | POLB (0.59) | MEN1KMT2AMAPTPOLBTDP1 | |
| SCHEMBL31411587 | 0.71 | MAPT (0.67) | KMT2AMAPTPOLBTDP1HPGD | |
| SCHEMBL17263340 | 0.71 | ALDH1A1 (0.53) | MEN1KMT2AMAPTPOLBTDP1 | |
| SCHEMBL20339802 | 0.70 | GSK3B (0.63) | GSK3AGSK3BMEN1KMT2AMAPT | |
| SCHEMBL20339669 | 0.70 | GSK3A (0.68) | GSK3AGSK3BMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11649231-B2 | Compound as mTOR inhibitor and use thereof | MEDICINAL BIOCONVERGENCE RESEARCH CENTER (KR) | 2023-05-16 | — | — | US | disclosed |
| US-20210292314-A1 | NOVEL COMPOUND AS mTOR INHIBITOR AND USE THEREOF | MEDICINAL BIOCONVERGENCE RESEARCH CENTER (KR) | 2021-09-23 | — | — | US | disclosed |
| EP-3786163-A1 | NOVEL COMPOUND AS MTOR INHIBITOR AND USE THEREOF | Medicinal Bioconvergence Research Center (KR) | 2021-03-03 | — | — | EP | disclosed |
| CN-112368279-A | Novel compounds as mTOR inhibitors and uses thereof | 医药生命融合研究团 | 2021-02-12 | — | — | CN | disclosed |
| EP-1653954-A1 | ANTIBIOTIC THIAZOLIDINES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005020990-A1 | ANTIBIOTIC THIAZOLIDINES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2005-03-10 | — | — | WO | disclosed |
| EP-0861843-B1 | Fluorescent ionophoric compounds with a cryptand/crown-ether portion and a coumarin portion, their preparation and their use for measuring metal cation concentrations | TERUMO CARDIOVASCULAR SYS (US) | 2004-07-14 | — | — | EP | disclosed |
| EP-1204671-B1 | FLUOROGENIC COMPOUNDS AND USES THEREFOR | 3M INNOVATIVE PROPERTIES CO (US) | 2003-12-03 | — | — | EP | disclosed |
| US-6566508-B2 | Compound for use in the accurate detection of food parasites | 3M INNOVATIVE PROPERTIES COMPANY | 2003-05-20 | — | — | US | disclosed |
| US-20020147317-A1 | Fluorogenic compounds and uses therefor | 3M INNOVATIVE PROPETIES COMPANY | 2002-10-10 | — | — | US | disclosed |
| US-6372895-B1 | USEFUL IN ASSAYING FOR BIOLOGICAL ACTIVITY | 3M INNOVATIVE PROPERTIES COMPANY | 2002-04-16 | — | — | US | disclosed |
| WO-2001010881-A1 | FLUOROGENIC COMPOUNDS AND USES THEREFOR | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2001-02-15 | — | — | WO | disclosed |
| WO-2000032598-A9 | METHODS AND COMPOSITIONS FOR TREATING INFLAMMATORY DISEASES UTILIZING INHIBITORS OF TUMOR NECROSIS FACTOR ACTIVITY | STRUCTURAL BIOINFORMATICS INC (US) | 2000-11-30 | — | — | WO | disclosed |
| WO-2000032598-A1 | METHODS AND COMPOSITIONS FOR TREATING INFLAMMATORY DISEASES UTILIZING INHIBITORS OF TUMOR NECROSIS FACTOR ACTIVITY | STRUCTURAL BIOINFORMATICS INC. (US) | 2000-06-08 | — | — | WO | disclosed |
| US-5958782-A | FLUORESCENT IONOPHORIC COMPOUND IS DISCLOSED THAT INCLUDES A COMPLEXING MOIETY, SUCH AS A CRYPTAND OR CROWN-ETHER PORTION, AND A FLUORESCING MOIETY SUCH AS A COUMARIN PORTION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-09-28 | — | — | US | disclosed |
| EP-0861843-A2 | Fluorescent ionophoric compounds with a cryptand/crown-ether portion and a coumarin portion, their preparation and their use for measuring metal cation concentrations | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-09-02 | — | — | EP | disclosed |
| US-5587279-A | HIGH CONCENTRATION OF SILVER CHLORIDE GRAINS | FUJI PHOTO FILM CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0185100-B1 | PROCESS FOR PREPARING SILVER HALIDE EMULSION | FUJI PHOTO FILM CO LTD (JP) | 1990-05-30 | — | — | EP | disclosed |
| US-4713321-A | SENSITIZING DYES, OXIDIZERS SUCH AS PEROXIDES | FUJI PHOTO FILM CO., LTD. (JP) | 1987-12-15 | — | — | US | disclosed |
| EP-0185100-A1 | PROCESS FOR PREPARING SILVER HALIDE EMULSION | FUJI PHOTO FILM CO., LTD. (JP) | 1986-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11649231-B2 | Compound as mTOR inhibitor and use thereof | MTOR, RICTOR, RPTOR | GSK3A 103/4885GSK3B 75/4885MEN1 855/4885 |
| US-20020147317-A1 | Fluorogenic compounds and uses therefor | NOTUM, WEE1, CPSF7 | GSK3A 2010/4885GSK3B 1872/4885MEN1 852/4885 |
| US-20210292314-A1 | NOVEL COMPOUND AS mTOR INHIBITOR AND USE THEREOF | MTOR, RICTOR, RPTOR | GSK3A 143/4885GSK3B 110/4885MEN1 1151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.