Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | APEX1 | P27695 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.61 |
| ▸ | MMP2 | P08253 | 1/20 | 0.61 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.61 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.61 |
| ▸ | HBB | P68871 | 1/20 | 0.61 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11157478 | 0.88 | MAPT (0.61) | KDM4EHTTMAPTMEN1POLB | |
| SCHEMBL17525779 | 0.79 | KDM4E (0.53) | KDM4EHTTMAPTMEN1POLB | |
| SCHEMBL2795967 | 0.78 | ALDH1A1 (0.54) | KDM4EMAPTMEN1POLBKMT2A | |
| SCHEMBL2115613 | 0.76 | MAPT (1.00) | KDM4EHTTMAPTMEN1POLB | |
| SCHEMBL480278 | 0.76 | ALDH1A1 (0.73) | KDM4EMAPTMEN1POLBKMT2A | |
| SCHEMBL5912905 | 0.75 | L3MBTL1 (0.49) | KDM4EHTTMAPTMEN1POLB | |
| SCHEMBL6805692 | 0.75 | TSHR (0.49) | KDM4EHTTMAPTMEN1POLB | |
| SCHEMBL5728014 | 0.75 | GSK3A (0.59) | KDM4EHTTMAPTMEN1POLB | |
| SCHEMBL11791001 | 0.74 | ALDH1A1 (0.54) | KDM4EHTTMAPTMEN1POLB | |
| SCHEMBL16277156 | 0.74 | SIGMAR1 (0.50) | KDM4EMEN1KMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210047282-A1 | REVERSIBLE CROSSLINKING REACTANT COMPOSITION | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2021-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210047282-A1 | REVERSIBLE CROSSLINKING REACTANT COMPOSITION | RRS1, CCNE2, RPS9 | KDM4E 280/4885HTT 2658/4885MAPT 2633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.