SCHEMBL5728110

SCHEMBL5728110

CCOC(=O)C(Cc1ccccc1)C(C)(CC)C(=O)OCC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 3/20 0.49
ALDH1A1 P00352 3/20 0.45
RECQL P46063 1/20 0.45
PIN1 Q13526 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
MAPT P10636 1/20 0.42
EPHX2 P34913 1/20 0.41
PPARG P37231 1/20 0.41
TP53 P04637 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
NPY1R P25929 1/20 0.41
NPY2R P49146 1/20 0.41
LMNA P02545 2/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
KMT2A Q03164 1/20 0.40
PPID Q08752 1/20 0.40
POLB P06746 1/20 0.40
HSD17B10 Q99714 1/20 0.40
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27094038 0.90 MMP8 (0.53) MMP8ALDH1A1RECQLPIN1SMN1; SMN2
SCHEMBL15930101 0.83 MMP8 (0.55) MMP8ALDH1A1RECQLPIN1SMN1; SMN2
SCHEMBL14770008 0.83 MMP8 (0.55) MMP8ALDH1A1RECQLPIN1SMN1; SMN2
SCHEMBL304717 0.83 MMP8 (0.49) MMP8ALDH1A1RECQLPIN1SMN1; SMN2
SCHEMBL5653528 0.77 MMP8 (0.52) MMP8ALDH1A1RECQLSMN1; SMN2MAPT
SCHEMBL5650006 0.77 MMP8 (0.52) MMP8ALDH1A1RECQLSMN1; SMN2MAPT
SCHEMBL305289 0.77 MMP8 (0.46) MMP8ALDH1A1RECQLPIN1SMN1; SMN2
SCHEMBL14874582 0.77 ITGA4 (0.43) MMP8ALDH1A1RECQLPIN1SMN1; SMN2
SCHEMBL5651363 0.77 MMP8 (0.51) MMP8ALDH1A1PIN1SMN1; SMN2MAPT
SCHEMBL5651688 0.77 MMP8 (0.51) MMP8ALDH1A1PIN1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1294159-C Propylene polymers with high isotactic index BASSEL TECHNOLOGY B V (NL) 2007-01-10 CN disclosed
EP-1088009-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SRL (IT) 2006-08-02 EP disclosed
CN-1240729-C Components and catalysts for the polymerization of olefins BASELL TECHNOLOGY CO B V (IT) 2006-02-08 CN disclosed
US-20050032633-A1 Propylene polymers BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2005-02-10 US disclosed
US-6818583-B1 HIGH YIELDS AND HIGH ISOTACTIC INDEX; COMPRISING MG, TI, HALOGEN AND A SUCCINATE ELECTRON DONOR BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-11-16 US disclosed
CN-1515597-A Propylene polymers with high isotactic index 2004-07-28 CN disclosed
CN-1313869-A Components and catalysts for the polymerization of olefins BASELL TECHNOLOGY CO B V (NL) 2001-09-19 CN disclosed