Toluene

Toluene

SCHEMBL57282

Cc1ccccc1.Cc1ccccc1.N=C=O.N=C=O

nearest known ligand 0.65

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.65
TSHR P16473 2/20 0.65
LMNA P02545 2/20 0.65
ALOX12 P18054 1/20 0.65
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
HPGD P15428 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
NPC1 O15118 4/20 0.38
RAB9A P51151 4/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
VCP P55072 1/20 0.38
BCHE P06276 1/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
ALDH1A1 P00352 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
MTOR P42345 1/20 0.36
CA12 O43570 2/20 0.35
CA9 Q16790 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL11099704 1.00 ACHE (0.65) ACHETSHRLMNAALOX12CES2
Toluene SCHEMBL28853719 1.00 ACHE (0.65) ACHETSHRLMNAALOX12CES2
Toluene SCHEMBL240812 1.00 ACHE (0.65) ACHETSHRLMNAALOX12CES2
Toluene SCHEMBL29997697 1.00 ACHE (0.65) ACHETSHRLMNAALOX12CES2
Toluene SCHEMBL28488283 1.00 ACHE (0.65) ACHETSHRLMNAALOX12CES2
Toluene SCHEMBL32871 1.00 ACHE (0.65) ACHETSHRLMNAALOX12CES2
Toluene SCHEMBL1132376 1.00 ACHE (0.65) ACHETSHRLMNAALOX12CES2
Toluene SCHEMBL7745465 1.00 ACHE (0.65) ACHETSHRLMNAALOX12CES2
Toluene SCHEMBL29088577 1.00 ACHE (0.65) ACHETSHRLMNAALOX12CES2
Toluene SCHEMBL28174229 1.00 ACHE (0.65) ACHETSHRLMNAALOX12CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4771 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118355088-A Moisture-curable polyurethane hot melt adhesive compositions 汉高股份有限及两合公司 2024-07-16 CN claimed
US-12031065-B2 Adhesive composition comprising a polyurethane and a cationic dopant E INK CORPORATION (US) 2024-07-09 US claimed
US-20240218221-A1 Moisture-Curable Polyurethane Hot Melt Adhesive Composition HENKEL AG & CO KGAA (DE) 2024-07-04 US claimed
CN-115850694-B Polymeric carbodiimide compound hydrolysis-resistant agent and preparation method and application thereof 上海朗亿功能材料有限公司 2024-06-18 CN claimed
CN-118185431-A Environment-friendly paint for inner and outer walls of corrosion-resistant cast iron drain pipe, and preparation method and application thereof 湖北三雷德化工有限公司 2024-06-14 CN claimed
EP-3250619-B1 FUNCTIONALIZED POLYURETHANES PREPARED FROM RENEWABLE MATERIALS HENKEL AG & CO KGAA (DE) 2024-04-24 EP claimed
WO-2024056945-A1 THICKENING CYCLO-ALKYLATED URETHANE COPOLYMER COATEX (FR) 2024-03-21 WO claimed
WO-2024038104-A1 THERMOPLASTIC POLYURETHANE MATERIALS HAVING GOOD ELASTIC RECOVERY AND LOW SOFTENING TEMPERATURE HUNTSMAN INTERNATIONAL LLC (US) 2024-02-22 WO claimed
CN-116515450-B Polyurethane pouring sealant and preparation method thereof 广州市百舜合成材料有限公司 2024-01-30 CN claimed
CN-115572573-B Polyurethane hot melt adhesive for intelligent wearing and preparation method thereof 深圳市优威高乐技术有限公司 2023-12-19 CN claimed
US-5824738-A AUTOMOTIVE TRIM, CONTROLLED MIXTURE OF HINDERED AMINE STABILIZER, BENZOTRIAZOLE STABILIZER, ANTIOXIDANT AND PIGMENT, WEATHER RESISTANCE DAVIDSON TEXTRON INC. (US) 1998-10-20 US claimed
WO-1997042246-A1 POLYURETHANE COMPOSITION USEFUL FOR COATING CYLINDRICAL PARTS UNIROYAL CHEMICAL COMPANY, INC. (US) 1997-11-13 WO claimed
EP-0712887-A2 Light stable aliphatic thermoplastic urethane elastomers and method of making same DAVIDSON TEXTRON INC. (US) 1996-05-22 EP claimed
US-5371133-A Polymerizing polyurethane in acrylic or vinyl monomer that acts as solvent, then polymerizing the addition polymer; no urea linkages NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1994-12-06 US claimed
CN-1087919-A Polymer-modified polyol dispersions and production method thereof and purposes WOODBRIDGE FOAM CORP (CA) 1994-06-15 CN claimed
US-5290623-A Substrate; hot-melt ink layer of polyether with bisphenol skeleton and terminal hydroxyls, colorant; release layer of silicone resin, fatty acid or salt or derivative, alcohol or wax; back-coated layer of aminosilicone-polyisocyanate product KAO CORPORATION (JP) 1994-03-01 US claimed
EP-0188324-B1 MAGNETIC COATING COMPRISING ELECTRON BEAM CURABLE POLYURETHANES MORTON INTERNATIONAL, INC. (US) 1992-04-01 EP claimed
US-4695604-A Electron beam curable polyuethane polymers for magnetic tape applications MORTON THIOKOL, INC. (US) 1987-09-22 US claimed
EP-0188324-A2 Magnetic coating comprising electron beam curable polyurethanes MORTON INTERNATIONAL, INC. (US) 1986-07-23 EP claimed
US-4239878-A CORROSION RESISTANT COATINGS MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1980-12-16 US claimed