Sugi Predict

Sugi Predict / Compounds / Toluene

Toluene

Toluene

SCHEMBL1132376

Cc1ccccc1.N=C=O.N=C=O.N=C=O.N=C=O

nearest known ligand 0.65

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ACHE P22303 5/20 0.65
▸ TSHR P16473 2/20 0.65
▸ LMNA P02545 2/20 0.65
▸ ALOX12 P18054 1/20 0.65
▸ CES2 O00748 1/20 0.42
▸ CES1 P23141 1/20 0.42
▸ HPGD P15428 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.39
▸ NPC1 O15118 4/20 0.38
▸ RAB9A P51151 4/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ VCP P55072 1/20 0.38
▸ BCHE P06276 1/20 0.36
▸ SMN1; SMN2 Q16637 4/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ NPSR1 Q6W5P4 1/20 0.36
▸ MTOR P42345 1/20 0.36
▸ CA12 O43570 2/20 0.35
▸ CA9 Q16790 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL11099704 1.00 ACHE (0.65) ACHETSHRLMNAALOX12CES2
Toluene SCHEMBL28853719 1.00 ACHE (0.65) ACHETSHRLMNAALOX12CES2
Toluene SCHEMBL240812 1.00 ACHE (0.65) ACHETSHRLMNAALOX12CES2
Toluene SCHEMBL29997697 1.00 ACHE (0.65) ACHETSHRLMNAALOX12CES2
Toluene SCHEMBL28488283 1.00 ACHE (0.65) ACHETSHRLMNAALOX12CES2
Toluene SCHEMBL32871 1.00 ACHE (0.65) ACHETSHRLMNAALOX12CES2
Toluene SCHEMBL57282 1.00 ACHE (0.65) ACHETSHRLMNAALOX12CES2
Toluene SCHEMBL7745465 1.00 ACHE (0.65) ACHETSHRLMNAALOX12CES2
Toluene SCHEMBL29088577 1.00 ACHE (0.65) ACHETSHRLMNAALOX12CES2
Toluene SCHEMBL28174229 1.00 ACHE (0.65) ACHETSHRLMNAALOX12CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024706-A Ultraviolet light cured modified organic silicon resin and preparation method thereof 深圳市康利邦科技有限公司 2023-11-10 — — CN claimed
CN-112239622-A Preparation method of waterborne polyurethane composite coating for glass substrate 长春工业大学 2021-01-19 — — CN claimed
CN-105983138-B A kind of hydrophilic lubrication polyurethane medical interposing catheter and preparation method thereof 北京迪玛克医药科技有限公司 2019-03-22 — — CN claimed
EP-1608694-B1 PROCESS FOR THE PREPARATION OF HIGH SOLIDS URETHANE ALKYDS PPG BV (NL) 2008-11-05 — — EP claimed
EP-0641844-A1 Distortion control additives for ultraviolet curable compositions UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1995-03-08 — — EP claimed
EP-4240311-B1 COMPOSITION FOR KERATIN FIBERS OREAL (FR) 2026-04-01 — — EP disclosed
US-20250107981-A1 METHODS FOR SMOOTHING HAIR L'OREAL (FR) 2025-04-03 — — US disclosed
US-20250107988-A1 HAIR TREATMENT COMPOSITION AND METHODS FOR SMOOTHING HAIR L'OREAL (FR) 2025-04-03 — — US disclosed
US-20250099352-A1 METHODS FOR REDUCING FRIZZ AND IMPROVING SMOOTHNESS OF HAIR L'OREAL (FR) 2025-03-27 — — US disclosed
US-20250099350-A1 HAIR TREATMENT METHODS FOR SMOOTHING HAIR L'OREAL (FR) 2025-03-27 — — US disclosed
US-20250099353-A1 METHODS FOR SMOOTHING HAIR L'OREAL (FR) 2025-03-27 — — US disclosed
US-20250099359-A1 METHODS FOR REDUCING FRIZZ AND IMPROVING SMOOTHNESS OF HAIR L'OREAL (FR) 2025-03-27 — — US disclosed
US-20050234144-A1 Prepolymers containing silyl groups, the production thereof and the use of the same in polyurethane foams HENKEL AG & CO. KGAA (DE) 2005-10-20 — — US disclosed
CN-1223790-C Surface light source system and light deflection element used therein MITSUBISHI RAYON CO (JP) 2005-10-19 — — CN disclosed
EP-1578866-A1 THERMOPLASTIC ELASTOMER RESIN Samyang Corporation (KR) 2005-09-28 — — EP disclosed
WO-2004058891-A1 THERMOPLASTIC ELASTOMER RESIN SAMYANG CORPORATION (KR) 2004-07-15 — — WO disclosed
CN-1479848-A Surface light source system and its used optical deflection element 三菱丽阳株式会社 2004-03-03 — — CN disclosed
US-20030225240-A1 Modified urethane compositions containing adducts of O-phthalic anhydride ester polyols UNIROYAL CHEMICAL COMPANY, INC. 2003-12-04 — — US disclosed
US-5145935-A Having difunctional chain extender; melt processability; not shape restricted MITSUBISHI JUKOGYO KABUSHIKI KAISHA (JP) 1992-09-08 — — US disclosed
US-5128197-A Polyurethane MITSUBISHI JUKOGYO KABUSHIKI KAISHA (JP) 1992-07-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250099350-A1 HAIR TREATMENT METHODS FOR SMOOTHING HAIR KDM7A, KDM5C, KCNC1 ACHE 4244/4885TSHR 2404/4885LMNA 1188/4885
US-20250099352-A1 METHODS FOR REDUCING FRIZZ AND IMPROVING SMOOTHNESS OF HAIR FZD7, SHH, FGFR3 ACHE 4636/4885TSHR 2643/4885LMNA 1894/4885
US-20250099359-A1 METHODS FOR REDUCING FRIZZ AND IMPROVING SMOOTHNESS OF HAIR FLNA, FZD7, KRT18 ACHE 4062/4885TSHR 2909/4885LMNA 2702/4885
US-20250099353-A1 METHODS FOR SMOOTHING HAIR CD99, CD44, CA13 ACHE 3278/4885TSHR 3806/4885LMNA 1617/4885
US-20250107988-A1 HAIR TREATMENT COMPOSITION AND METHODS FOR SMOOTHING HAIR FZD7, DSC1, COL14A1 ACHE 4320/4885TSHR 2304/4885LMNA 1197/4885
US-20250107981-A1 METHODS FOR SMOOTHING HAIR FZD7, CROCC, DSC1 ACHE 3731/4885TSHR 3571/4885LMNA 1827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.