Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 11/20 | 0.38 |
| ▸ | CCKAR | P32238 | 6/20 | 0.38 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.30 |
| ▸ | ACLY | P53396 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3899517 | 1.00 | CCKBR (0.38) | CCKBRCCKARLIMK2L3MBTL1GAA | |
| SCHEMBL3902088 | 0.92 | CCKBR (0.33) | CCKBRCCKAR | |
| SCHEMBL5728424 | 0.91 | LIMK2 (0.36) | LIMK2EGLN1GHSRACLY | |
| SCHEMBL3900580 | 0.91 | LIMK2 (0.36) | LIMK2EGLN1GHSRACLY | |
| SCHEMBL3902462 | 0.91 | LIMK2 (0.38) | LIMK2EGLN1GHSR | |
| SCHEMBL5443012 | 0.91 | CCKBR (0.36) | CCKBRCCKARLIMK2EGLN1ACLY | |
| SCHEMBL3900502 | 0.91 | CCKBR (0.36) | CCKBRCCKARLIMK2EGLN1ACLY | |
| SCHEMBL3902484 | 0.91 | CCKBR (0.36) | CCKBRCCKARLIMK2EGLN1ACLY | |
| SCHEMBL3900162 | 0.88 | USP2 (0.35) | LIMK2ACLY | |
| SCHEMBL3904144 | 0.86 | L3MBTL1 (0.47) | CCKBRCCKARL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675837-A2 | BENZO [1,2,5] THIADIAZOLE COMPOUNDS AS CCK2 MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005012275-A2 | BENZO [1, 2, 5] THIADIAZOLE COMPOUNDS AS CCK2 MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-02-10 | — | — | WO | disclosed |