SCHEMBL5728295

SCHEMBL5728295

CCCOC(=O)CC(C)C(=O)OCCC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
MAPK1 P28482 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
NAAA Q02083 1/20 0.38
DGKA P23743 1/20 0.38
ALDH1A1 P00352 5/20 0.37
HCAR2 Q8TDS4 1/20 0.36
LMNA P02545 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ESR1 P03372 1/20 0.33
CHRM1 P11229 1/20 0.33
TSHR P16473 1/20 0.33
SLC6A2 P23975 1/20 0.33
KDR P35968 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PPM1B O75688 1/20 0.33
PTPN1 P18031 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21474557 0.92 MGAM (0.43) MAPTNPSR1MAPK1L3MBTL1ALDH1A1
SCHEMBL5728492 0.88 NAAA (0.48) MAPTNPSR1MAPK1L3MBTL1NAAA
SCHEMBL12526876 0.88 CA1 (0.37) MAPTNPSR1MAPK1L3MBTL1NAAA
SCHEMBL15491411 0.86 NAAA (0.57) MAPTNPSR1MAPK1L3MBTL1NAAA
SCHEMBL12526880 0.86 NAAA (0.57) MAPTNPSR1MAPK1L3MBTL1NAAA
SCHEMBL4548423 0.85 HCAR2 (0.39) NAAADGKAALDH1A1HCAR2LMNA
SCHEMBL21474644 0.84 NAAA (0.60) MAPTNPSR1MAPK1L3MBTL1NAAA
SCHEMBL14587119 0.84 NAAA (0.60) MAPTNPSR1MAPK1L3MBTL1NAAA
SCHEMBL21478224 0.84 NAAA (0.60) MAPTNPSR1MAPK1L3MBTL1NAAA
SCHEMBL12524471 0.84 NAAA (0.60) MAPTNPSR1MAPK1L3MBTL1NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102372797-A Catalyst components for olefin polymerization and catalyst thereof CHINA PETROLEUM & CHEMICAL 2012-03-14 CN claimed
US-5563290-A Method for preparing optically active succinic acid compound NIPPON OIL CO. LTD. (JP) 1996-10-08 US claimed
CN-108024950-B Method for enriching phellinus igniarius seed element of karanja oil 碧昂赛恩斯公司 2021-05-11 CN disclosed
EP-2683351-B1 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME OREAL (FR) 2019-10-16 EP disclosed
US-10245220-B2 Process for pongamol enrichment of karanja oil BIOSYNTHIS (FR) 2019-04-02 US disclosed
US-20180207070-A1 PROCESS FOR PONGAMOL ENRICHMENT OF KARANJA OIL BIOSYNTHIS (FR) 2018-07-26 US disclosed
EP-3325103-A1 PROCESS FOR PONGAMOL ENRICHMENT OF KARANJA OIL Biosynthis (FR) 2018-05-30 EP disclosed
US-20160067160-A1 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME OREAL (FR) 2016-03-10 US disclosed
US-20160067160-A1 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME OREAL (FR) 2016-03-10 US disclosed
EP-2983233-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTRICITY STORAGE DEVICE USING SAME UBE Industries, Ltd. (JP) 2016-02-10 EP disclosed
US-20140056832-A1 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME L'OREAL (FR) 2014-02-27 US disclosed
US-20140056832-A1 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME L'OREAL (FR) 2014-02-27 US disclosed
WO-2012119861-A2 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME L'OREAL (FR) 2012-09-13 WO disclosed
EP-1088009-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SRL (IT) 2006-08-02 EP disclosed
US-5563290-A Method for preparing optically active succinic acid compound NIPPON OIL CO. LTD. (JP) 1996-10-08 US disclosed
EP-0663382-A1 Process for preparing optically active succinic acid compound NIPPON OIL CO. LTD. (JP) 1995-07-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10245220-B2 Process for pongamol enrichment of karanja oil CBX3, PAOX, CBX8 MAPT 4140/4885NPSR1 1982/4885MAPK1 2099/4885
US-20140056832-A1 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME DIMT1, MAT2A, SCD MAPT 3962/4885NPSR1 3426/4885MAPK1 2289/4885
US-20160067160-A1 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME DIMT1, FADS2, SCD MAPT 3804/4885NPSR1 3517/4885MAPK1 2124/4885
US-20180207070-A1 PROCESS FOR PONGAMOL ENRICHMENT OF KARANJA OIL CBX3, PAOX, CBX8 MAPT 4140/4885NPSR1 1982/4885MAPK1 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.