SCHEMBL5728403

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5728402	1.00	PDGFRB (0.80)	PDGFRBPDPK1KDRFLT3KIT
	SCHEMBL3912682	0.89	PDGFRB (1.00)	PDGFRBPDPK1KDRFLT3RET
	SCHEMBL3912686	0.89	PDGFRB (1.00)	PDGFRBPDPK1KDRFLT3RET
	SCHEMBL5728570	0.83	PDPK1 (1.00)	PDGFRBPDPK1KDRFLT3KIT
	SCHEMBL396432	0.83	PDGFRB (0.71)	PDGFRBPDPK1KDRFLT3KIT
	SCHEMBL5728607	0.83	PDPK1 (0.80)	PDGFRBPDPK1KDRFLT3KIT
	SCHEMBL5728251	0.83	PDGFRB (1.00)	PDGFRBPDPK1KDRFLT3RET
	SCHEMBL396431	0.83	PDGFRB (0.71)	PDGFRBPDPK1KDRFLT3KIT
	SCHEMBL5728610	0.83	PDPK1 (0.80)	PDGFRBPDPK1KDRFLT3KIT
	SCHEMBL5728571	0.83	PDPK1 (1.00)	PDGFRBPDPK1KDRFLT3KIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.