Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
| ▸ | FNTB | P49356 | 1/20 | 0.50 |
| ▸ | SETD7 | Q8WTS6 | 4/20 | 0.46 |
| ▸ | DRD3 | P35462 | 4/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682349 | 0.87 | FNTA (0.53) | FNTAFNTBSETD7DRD3CHRM2 | |
| SCHEMBL9844279 | 0.84 | FNTA (0.54) | FNTAFNTBSETD7DRD3CHRM2 | |
| Hydrochloric Acid SCHEMBL5728654 | 0.84 | DRD3 (0.61) | FNTAFNTBDRD3HTR1ADRD2 | |
| SCHEMBL5729262 | 0.84 | LMNA (0.52) | FNTAFNTBSETD7DRD3CHRM2 | |
| SCHEMBL7674794 | 0.84 | FNTA (0.55) | FNTAFNTBSETD7DRD3CHRM2 | |
| SCHEMBL9844244 | 0.83 | FNTA (0.53) | FNTAFNTBSETD7DRD3CHRM2 | |
| SCHEMBL9844384 | 0.83 | FNTA (0.53) | FNTAFNTBSETD7DRD3CHRM2 | |
| Hydrochloric Acid SCHEMBL9844374 | 0.83 | FNTA (0.53) | FNTAFNTBSETD7DRD3CHRM2 | |
| SCHEMBL9844251 | 0.83 | FNTA (0.53) | FNTAFNTBSETD7DRD3CHRM2 | |
| SCHEMBL7676763 | 0.83 | FNTA (0.55) | FNTAFNTBSETD7DRD3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044197-B1 | PIPERIDINYL-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKYNE CARBOXAMIDES AS CYTOSTATIC AGENTS AND IMMUNOSUPPRESSANTS | ASTELLAS PHARMA GMBH (DE) | 2006-04-19 | — | — | EP | disclosed |
| US-6593344-B1 | These substances have especially high cytostatic activities and pronounced immunosuppressive properties which make them suitable for therapeutic treatment in broad tumor spectrum and autoimmune diseases | KLINGE PHARMA GMBH (DE) | 2003-07-15 | — | — | US | disclosed |