Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9146077 | 0.77 | MEN1 (0.38) | CNR1CNR2 | |
| SCHEMBL9255825 | 0.74 | TAAR1 (0.33) | — | |
| SCHEMBL27351178 | 0.67 | KDM4E (0.30) | — | |
| SCHEMBL9749322 | 0.66 | KDM4E (0.43) | CNR1CNR2 | |
| SCHEMBL13952741 | 0.64 | L3MBTL1 (0.35) | CNR1CNR2 | |
| SCHEMBL11727643 | 0.60 | HRH1 (0.39) | HRH1HRH4 | |
| SCHEMBL9254332 | 0.60 | L3MBTL1 (0.34) | — | |
| SCHEMBL18361627 | 0.59 | TRPV1 (0.41) | CNR1CNR2 | |
| SCHEMBL9382459 | 0.59 | ALDH1A1 (0.34) | — | |
| SCHEMBL9146295 | 0.59 | IDO1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135394-B1 | SPIROCYCLIC THIENOPYRANS AS POTASSIUM CHANNEL ACTIVATORS | CAMBRIDGE BIOCLINICAL LTD (GB) | 2006-03-01 | — | — | EP | disclosed |
| US-6342517-B1 | THIENOPYRAN COMPOUNDS AS HYPOTENSIVE AGENTS | CAMBRIDGE BIOCLINICAL LIMITED (GB) | 2002-01-29 | — | — | US | disclosed |