SCHEMBL5729082

SCHEMBL5729082

CCOC(=O)C(C(C)C)C(CC)(C(=O)OCC)C(C)C

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.37
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CYP4F2 P78329 2/20 0.35
CYP4A11 Q02928 2/20 0.35
PKM P14618 3/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
THRB P10828 1/20 0.32
HTT P42858 1/20 0.31
ALOX15 P16050 1/20 0.30
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30
SOAT1 P35610 1/20 0.30
PIN1 Q13526 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3922343 0.88 MMP8 (0.36) MMP8ALDH1A1LMNAHSD17B10CYP4F2
SCHEMBL29094060 0.87 MMP8 (0.44) MMP8ALDH1A1LMNAHSD17B10CYP4F2
SCHEMBL26107094 0.86 MMP8 (0.45) MMP8ALDH1A1LMNAHSD17B10CYP4F2
SCHEMBL1785473 0.79 MMP8 (0.37) MMP8ALDH1A1LMNAHSD17B10CYP4F2
SCHEMBL1785797 0.76 MMP8 (0.41) MMP8ALDH1A1LMNAHSD17B10CYP4F2
SCHEMBL13269393 0.76 MMP8 (0.38) MMP8ALDH1A1LMNAHSD17B10CYP4F2
SCHEMBL15034664 0.74 ALDH1A1 (0.46) MMP8ALDH1A1LMNAHSD17B10CYP4F2
SCHEMBL13821863 0.74 ALDH1A1 (0.46) MMP8ALDH1A1LMNAHSD17B10CYP4F2
SCHEMBL14770006 0.74 ALDH1A1 (0.46) MMP8ALDH1A1LMNAHSD17B10CYP4F2
SCHEMBL13269549 0.74 MMP8 (0.36) MMP8ALDH1A1LMNAHSD17B10CYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11186660-B2 Internal electron donor compound for preparing α-olefin polymerization catalyst component YINGKOU XIANGYANG CATALYST CO., LTD. 2021-11-30 US claimed
US-20190218317-A1 INTERNAL ELECTRON DONOR COMPOUND FOR PREPARING ALPHA-OLEFIN POLYMERIZATION CATALYST COMPONENT YINGKOU XIANGYANG CATALYST CO LTD (CN) 2019-07-18 US claimed
US-10287371-B2 Internal electron donor compound for preparing α-olefin polymerization catalyst component YINGKOU XIANGYANG CATALYST CO., LTD. (CN) 2019-05-14 US claimed
US-20160229935-A1 Internal Electron Donor Compound for Preparing Alpha-olefin Polymerization Catalyst Component DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2016-08-11 US claimed
US-11186660-B2 Internal electron donor compound for preparing α-olefin polymerization catalyst component YINGKOU XIANGYANG CATALYST CO., LTD. 2021-11-30 US disclosed
US-20190218317-A1 INTERNAL ELECTRON DONOR COMPOUND FOR PREPARING ALPHA-OLEFIN POLYMERIZATION CATALYST COMPONENT YINGKOU XIANGYANG CATALYST CO LTD (CN) 2019-07-18 US disclosed
US-10287371-B2 Internal electron donor compound for preparing α-olefin polymerization catalyst component YINGKOU XIANGYANG CATALYST CO., LTD. (CN) 2019-05-14 US disclosed
US-20160229935-A1 Internal Electron Donor Compound for Preparing Alpha-olefin Polymerization Catalyst Component DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2016-08-11 US disclosed
EP-1088009-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SRL (IT) 2006-08-02 EP disclosed
US-20050032633-A1 Propylene polymers BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2005-02-10 US disclosed
US-6818583-B1 HIGH YIELDS AND HIGH ISOTACTIC INDEX; COMPRISING MG, TI, HALOGEN AND A SUCCINATE ELECTRON DONOR BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-11-16 US disclosed