Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 6/20 | 0.41 |
| ▸ | F10 | P00742 | 13/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5729062 | 0.84 | F10 (0.41) | F10F2 | |
| SCHEMBL5729275 | 0.82 | HSD11B1 (0.37) | RORC | |
| SCHEMBL5729315 | 0.77 | F10 (0.53) | F10 | |
| SCHEMBL5729645 | 0.77 | F10 (0.44) | F10F2 | |
| SCHEMBL5735437 | 0.76 | F10 (0.41) | RORCF10F2 | |
| SCHEMBL5735439 | 0.76 | F10 (0.41) | RORCF10F2 | |
| SCHEMBL5729156 | 0.75 | F10 (0.49) | F10F2 | |
| SCHEMBL5730186 | 0.74 | F10 (0.47) | F10F2 | |
| SCHEMBL6730470 | 0.73 | GLRA3 (0.43) | F10F2 | |
| SCHEMBL6730840 | 0.73 | GLRA3 (0.43) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188755-B1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-6723722-B1 | BLOOD COAGULATION FACTOR X INHIBITORS; ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-20 | — | — | US | disclosed |
| EP-1188755-A1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-03-20 | — | — | EP | disclosed |