Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5730186 | 0.84 | F10 (0.47) | F10F2 | |
| SCHEMBL5728864 | 0.83 | STS (0.47) | F10SMN1; SMN2 | |
| SCHEMBL5728996 | 0.83 | STS (0.48) | F10 | |
| SCHEMBL5729524 | 0.82 | F10 (0.43) | F10F2 | |
| SCHEMBL6895069 | 0.81 | F10 (0.44) | F10SMN1; SMN2 | |
| SCHEMBL7055121 | 0.79 | DRD2 (0.44) | F10POLBSMN1; SMN2 | |
| SCHEMBL6887955 | 0.79 | DRD2 (0.44) | F10POLBSMN1; SMN2 | |
| SCHEMBL5728783 | 0.79 | APP (0.44) | F10 | |
| SCHEMBL5729520 | 0.78 | F10 (0.44) | F10F2 | |
| SCHEMBL5729219 | 0.78 | TGM2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188755-B1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-6723722-B1 | BLOOD COAGULATION FACTOR X INHIBITORS; ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-20 | — | — | US | disclosed |
| EP-1188755-A1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-03-20 | — | — | EP | disclosed |