Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | KYNU | Q16719 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | CTSS | P25774 | 3/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115471 | 0.93 | KYNU (0.63) | ALDH1A1ALOX15KYNUCTSKCTSL | |
| SCHEMBL4346138 | 0.93 | KYNU (0.63) | ALDH1A1ALOX15KYNUCTSKCTSL | |
| SCHEMBL3258258 | 0.93 | KYNU (0.63) | ALDH1A1ALOX15KYNUCTSKCTSL | |
| Hydrochloric Acid SCHEMBL3258256 | 0.92 | KYNU (0.62) | ALDH1A1ALOX15KYNUCTSKCTSL | |
| Hydrochloric Acid SCHEMBL3603219 | 0.92 | KYNU (0.62) | ALDH1A1ALOX15KYNUCTSKCTSL | |
| Hydrochloric Acid SCHEMBL3603216 | 0.92 | KYNU (0.62) | ALDH1A1ALOX15KYNUCTSKCTSL | |
| Trifluoroacetic Acid SCHEMBL7214280 | 0.90 | ALDH1A1 (0.56) | ALDH1A1ALOX15KYNUCTSKCTSL | |
| Trifluoroacetic Acid SCHEMBL7214279 | 0.90 | ALDH1A1 (0.56) | ALDH1A1ALOX15KYNUCTSKCTSL | |
| Trifluoroacetic Acid SCHEMBL23525220 | 0.86 | ALDH1A1 (0.58) | ALDH1A1ALOX15KYNUCTSKCTSL | |
| Trifluoroacetic Acid SCHEMBL23525223 | 0.86 | ALDH1A1 (0.58) | ALDH1A1ALOX15KYNUCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188755-B1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-6723722-B1 | BLOOD COAGULATION FACTOR X INHIBITORS; ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-20 | — | — | US | disclosed |
| EP-1188755-A1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-03-20 | — | — | EP | disclosed |