Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.35 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.35 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.35 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11132268 | 0.77 | IDO1 (0.45) | NCF1ADRB2CYP2D6CYP2C19OPRD1 | |
| SCHEMBL11016854 | 0.76 | NCF1 (0.41) | NCF1ADRB2CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL10732029 | 0.73 | NCF1 (0.43) | NCF1ADRB2CYP2D6CYP2C19OPRD1 | |
| SCHEMBL740828 | 0.72 | HTR2C (0.50) | ADRB2CYP2D6CYP2C19CYP3A4MAPT | |
| SCHEMBL10869952 | 0.72 | ADRB2 (0.42) | NCF1ADRB2CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL1702617 | 0.71 | SLC6A2 (0.42) | SLC6A2SLC6A4 | |
| SCHEMBL17448387 | 0.71 | CYP2D6 (0.46) | CYP2D6CYP2C19CYP3A4MAPTSLC6A4 | |
| SCHEMBL10738025 | 0.71 | ADRB2 (0.41) | NCF1ADRB2CYP2D6CYP2C19OPRD1 | |
| SCHEMBL6518202 | 0.70 | CYP2D6 (0.46) | NCF1CYP2D6CYP2C19CYP3A4MAPT | |
| SCHEMBL10868811 | 0.70 | CHRM1 (0.48) | NCF1ADRB2CYP2D6CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695964-A1 | Quinoline derivatives for use as intermediates in the synthesis of heterocyclylalcoyl piperidines | NOVEXEL (FR) | 2006-08-30 | — | — | EP | disclosed |