Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799065 | 0.89 | GPR119 (0.45) | GPR119USP30HIF1AALDH1A1HRH3 | |
| SCHEMBL5730616 | 0.89 | NR1H2 (0.42) | GPR119USP30ALDH1A1NR1H2NR1H3 | |
| SCHEMBL5729107 | 0.86 | NR1H2 (0.38) | GPR119USP30ALDH1A1NR1H2NR1H3 | |
| SCHEMBL38661200 | 0.73 | USP30 (0.47) | GPR119USP30HIF1AALDH1A1NR1H2 | |
| SCHEMBL25606205 | 0.73 | NR1H2 (0.63) | GPR119USP30HIF1AALDH1A1NR1H2 | |
| SCHEMBL5730431 | 0.73 | F10 (0.55) | — | |
| Hydrochloric Acid SCHEMBL5729006 | 0.72 | F10 (0.54) | — | |
| SCHEMBL13587106 | 0.71 | MAPT (0.63) | GPR119HIF1AALDH1A1HRH3 | |
| SCHEMBL1456142 | 0.71 | CKS1B (0.54) | GPR119 | |
| SCHEMBL25336906 | 0.70 | PDE4B (0.43) | ALDH1A1NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188755-B1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-6723722-B1 | BLOOD COAGULATION FACTOR X INHIBITORS; ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-20 | — | — | US | disclosed |
| EP-1188755-A1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-03-20 | — | — | EP | disclosed |