Oxalic Acid

Oxalic Acid

SCHEMBL5729545

C1=CC=CNC=C1.O=C(O)C(=O)O

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

OPRM1SLC6A4

The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL27759376 0.84 FFAR3 (0.44)
Carbamic Acid SCHEMBL27422028 0.84 ACHE (0.44)
Carbamic Acid SCHEMBL28313671 0.81 ACHE (0.41)
Maleic Acid SCHEMBL8714135 0.79 TSHR (0.50)
Fumaric Acid SCHEMBL8352060 0.79 TSHR (0.50)
Fumaric Acid SCHEMBL8352067 0.79 TSHR (0.50)
Succinic Acid SCHEMBL2578311 0.79 LMNA (0.50)
Benzene SCHEMBL4632543 0.78
Benzene SCHEMBL28275615 0.78
Oxygen SCHEMBL27468735 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-52053877-A None JP disclosed
CN-1934088-A As 5-HT2c6-substituted 2,3,4, 5-tetrahydro-1H-benzo [ d ] receptor agonists]Aza * LILLY CO ELI (US) 2007-03-21 CN disclosed
EP-1720836-A1 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS ELI LILLY AND COMPANY (US) 2006-11-15 EP disclosed
WO-2005082859-A1 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS ELI LILLY AND COMPANY (US) 2005-09-09 WO disclosed
EP-0351856-A2 Thiazolo[5,4-b]azepine compounds Takeda Chemical Industries, Ltd. (JP) 1990-01-24 EP disclosed
EP-0058341-B1 AZEPINE DERIVATIVES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM Dr. Karl Thomae GmbH (DE) 1985-05-15 EP disclosed
JP-S5253877-A PROCES FOR REPARING NOVEL MORPHOLINE DERIVATIVES AND THEIR ACID ADDUCT S SUMITOMO CHEM CO LTD 1977-04-30 JP disclosed