SCHEMBL5729593

SCHEMBL5729593

Cl[SiH](Cl)C1CCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2684805 0.92
SCHEMBL8764683 0.89 ALDH1A1 (0.30)
SCHEMBL8798701 0.89 ALDH1A1 (0.30)
SCHEMBL1040155 0.89
SCHEMBL7026195 0.84
SCHEMBL1821658 0.69 ALDH1A1 (0.31)
SCHEMBL3207791 0.67
SCHEMBL1041349 0.67 ALDH1A1 (0.30)
SCHEMBL9012322 0.65
SCHEMBL7778470 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12221385-B2 Preceramic polymer grafted nanoparticles and methods of making and using same UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2025-02-11 US claimed
US-20230416159-A1 Preceramic Polymer Grafted Nanoparticles and Methods of Making and Using Same THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2023-12-28 US claimed
CN-113072576-B Chiral sildenafil, synthetic method and application 四川大学 2022-04-26 CN claimed
CN-111592652-B Preparation method of modified polymethylsilane 内蒙古三友化学有限公司 2022-03-25 CN claimed
US-20210230072-A1 Preceramic Polymer Grafted Nanoparticles and Methods of Making and Using Same GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2021-07-29 US claimed
CN-113072576-A Chiral sildenafil, synthetic method and application 四川大学 2021-07-06 CN claimed
CN-111592652-A Preparation method of modified polymethylsilane 内蒙古三友化学有限公司 2020-08-28 CN claimed
US-12221385-B2 Preceramic polymer grafted nanoparticles and methods of making and using same UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2025-02-11 US disclosed
US-20230416159-A1 Preceramic Polymer Grafted Nanoparticles and Methods of Making and Using Same THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2023-12-28 US disclosed
US-11807583-B2 Preceramic polymer grafted nanoparticles and methods of making and using same UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2023-11-07 US disclosed
CN-116514860-A Eight-membered spiro silafluorene derivative, preparation method and application thereof 同济大学 2023-08-01 CN disclosed
CN-113072576-B Chiral sildenafil, synthetic method and application 四川大学 2022-04-26 CN disclosed
CN-111592652-B Preparation method of modified polymethylsilane 内蒙古三友化学有限公司 2022-03-25 CN disclosed
US-6316654-B1 REACTION PRODUCT WITH METAL OXIDE CATALYST SUPPORT; ESTERIFICATION, ESTER INTERCHANGE, AMINATION; UREA, URETHANE, AND SILICONE FORMATION ATOFINA CHEMICALS, INC. 2001-11-13 US disclosed
US-6166235-A ORGANOTIN FUNCTIONALIZED SILANES ELF ATOCHEM NORTH AMERICA, INC. (US) 2000-12-26 US disclosed
US-6162755-A Heterogeneous organotin catalysts ELF ATOCHEM NORTH AMERICAN, INC. (US) 2000-12-19 US disclosed
EP-0937728-A2 Heterogeneous organotin catalysts ELF ATOCHEM NORTH AMERICA, INC. (US) 1999-08-25 EP disclosed
EP-0534700-B1 Process for cycloalkyl substitution of hydrogen containing silanes DOW CORNING (US) 1996-11-20 EP disclosed
EP-0534700-A1 Process for cycloalkyl substitution of hydrogen containing silanes DOW CORNING CORPORATION (US) 1993-03-31 EP disclosed
US-5118829-A Organoborane compound catalyst DOW CORNING CORPORATION (US) 1992-06-02 US disclosed