SCHEMBL8798701

SCHEMBL8798701

Cl[SiH](Cl)C1CCCCCC1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764683 1.00 ALDH1A1 (0.30) ALDH1A1HSD17B10
SCHEMBL1040155 1.00
SCHEMBL2684805 0.96
SCHEMBL5729593 0.89
SCHEMBL7026195 0.81
SCHEMBL1041349 0.79 ALDH1A1 (0.30) ALDH1A1HSD17B10
SCHEMBL1821658 0.74 ALDH1A1 (0.31) ALDH1A1
SCHEMBL7778470 0.73
SCHEMBL17386439 0.69 ALDH1A1 (0.33) ALDH1A1HSD17B10
SCHEMBL17386489 0.69 ALDH1A1 (0.33) ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0549226-B1 Sodium borohydride catalyzed disproportionation of cycloorganosilanes DOW CORNING (US) 1997-04-02 EP disclosed
EP-0534700-B1 Process for cycloalkyl substitution of hydrogen containing silanes DOW CORNING (US) 1996-11-20 EP disclosed
EP-0549226-A1 Sodium borohydride catalyzed disproportionation of cycloorganosilanes DOW CORNING CORPORATION (US) 1993-06-30 EP disclosed
EP-0534700-A1 Process for cycloalkyl substitution of hydrogen containing silanes DOW CORNING CORPORATION (US) 1993-03-31 EP disclosed
US-5136070-A Sodium borohydride catalyzed disproportionation of cycloorganosilanes DOW CORNING CORPORATION (US) 1992-08-04 US disclosed
US-5118829-A Organoborane compound catalyst DOW CORNING CORPORATION (US) 1992-06-02 US disclosed