SCHEMBL572998

SCHEMBL572998

Nc1ccccc1C(N)(c1ccccc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 3/20 0.59
CYP3A4 P08684 2/20 0.41
ALOX15 P16050 2/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ALDH1A1 P00352 3/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TSHR P16473 6/20 0.35
PIK3CA P42336 1/20 0.35
KIF11 P52732 1/20 0.34
TAAR1 Q96RJ0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL222895 0.85 KCNN4 (0.53) KCNN4CYP3A4ALOX15CASP1CASP7
SCHEMBL2356320 0.83 KCNN4 (0.48) KCNN4CYP3A4ALOX15CASP1CASP7
Hydrochloric Acid SCHEMBL27897779 0.83 KCNN4 (0.52) KCNN4CYP3A4ALOX15CASP1CASP7
SCHEMBL7806575 0.78 ALOX15 (0.43) KCNN4CYP3A4ALOX15CASP1CASP7
SCHEMBL11043875 0.78 ALOX15 (0.43) KCNN4CYP3A4ALOX15CASP1CASP7
SCHEMBL10510801 0.77 KCNN4 (0.42) KCNN4CYP3A4ALOX15CASP1CASP7
SCHEMBL10636658 0.77 KCNN4 (0.42) KCNN4CYP3A4ALOX15CASP1CASP7
SCHEMBL30940020 0.76 ALOX15 (0.41) KCNN4CYP3A4ALOX15CASP1CASP7
Triphenylmethanamine SCHEMBL115149 0.76 KCNN4 (1.00) KCNN4ALDH1A1TSHRKIF11TAAR1
SCHEMBL7584160 0.76 KCNN4 (0.52) KCNN4CYP3A4ALOX15CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116835564-A Preparation method, specific adsorption application and adsorption equipment of bone charcoal material 中国农业大学 2023-10-03 CN claimed
CN-115894866-A Modified aromatic amine curing agent for storage battery sealant and preparation method thereof 杭州得力科技股份有限公司 2023-04-04 CN claimed
CN-112198141-A Method for measuring trivalent arsenic by resonance scattering spectrometry 浙江科德生物科技有限公司 2021-01-08 CN claimed
CN-104987671-A Method for preparing composite material with high thermal conductivity by utilizing diamond powder UNIV GUILIN TECH GUT 2015-10-21 CN claimed
CN-102532486-A Liquid aromatic amine epoxy resin curing agent and preparation method thereof UNIV GUILIN TECH GUT 2012-07-04 CN claimed
CN-102532485-A High-heat conduction and high-toughness epoxy resin compound and preparation method thereof UNIV GUILIN TECH GUT 2012-07-04 CN claimed
US-7338535-B2 Process for rapid dyeing and rapid decoloration of human keratin fibres with certain direct dyes L'OREAL S.A. (FR) 2008-03-04 US claimed
WO-2007017601-A1 BACTERIAL CULTURE MEDIUM IN A MINIMUM INORGANIC MEDIUM, COMPRISING GENTISATE AND/OR ONE OF THE PRECURSORS THEREOF, AND USE OF 3-HYDROXYBENZOATE IN ONE SUCH MEDIUM INSTITUT PASTEUR (FR) 2007-02-15 WO claimed
EP-1415643-A1 Process for rapidly colouring and decouring human keratinic fibres with direct dyes L'OREAL (FR) 2004-05-06 EP claimed
US-20040078906-A1 Process for rapid dyeing and rapid decoloration of human keratin fibres with certain direct dyes L'OREAL S.A. (FR) 2004-04-29 US claimed
EP-0257523-B1 PROCESS FOR MANUFACTURING WATER SOLUBLE TRIPHENYLMETHANE DYE COMPOUNDS OF FOODSTUFF STANDARD BASF Aktiengesellschaft (DE) 1990-01-31 EP claimed
US-4775451-A ELECTROLYTICALLY OXIDIZING LEUCO COMPOUNDS TO THE CORRESPONDING DYES BASF AKTIENGESELLSCHAFT (DE) 1988-10-04 US claimed
EP-0198303-B1 ANODIC OXIDATION PROCESS OF WATER SOLUBLE LEUCOTRIPHENYL METHANE DYE COMPOUNDS BASF Aktiengesellschaft (DE) 1988-08-17 EP claimed
JP-1306858-A None JP disclosed
JP-59055437-A None JP disclosed
WO-2025151354-A1 PHOTO-CURABLE COMPOSITIONS HENKEL AG & CO. KGAA (DE) 2025-07-17 WO disclosed
US-3972890-A ACID CATALYST BAYER AKTIENGESELLSCHAFT (DT) 1976-08-03 US disclosed
US-3960887-A Continuous process for the preparation of maleimides RHONE-POULENC S.A. (FR) 1976-06-01 US disclosed
US-3948598-A Black-dyeing process of basic dyeable polyester fibers SUMITOMO CHEMICAL CO., LTD. (JA) 1976-04-06 US disclosed
US-3947493-A Process for the production of maleamic acids RHONE-POULENC, S.A. (FR) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040078906-A1 Process for rapid dyeing and rapid decoloration of human keratin fibres with certain direct dyes KRT18, CYBA, TYR KCNN4 895/4885CYP3A4 835/4885ALOX15 3500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.